In this paper, the performances of a novel hybrid solar system using the Al2O3 nanofluid and pure water as a heat transfer fluid to operate a single-effect lithium bromide absorption chiller is investigated. In which the performance of the proposed system using the nanofluid during winter and summer under mixed and forced convection are evaluated. In which, the performances of solar collector are investigated experimentally, and the output performances of the water-LiBr absorption chiller system is conducted numerically using MATLAB platform. The results show that the obtained Reynolds number of the heat transfer fluid is laminar flow in summer with the maximum values 1700and 1600 for nanofluid and water, respectively; and transitory flow in winter with the maximum values of 2200 and 2100 for nanofluid and pure water, respectively. The proposed hybrid system achieves approximately 54%, 36%of maximum thermal efficiency during the winter and the summer, respectively. The obtained performance show that the absorption cycle at positive evaporation temperatures is very appreciable using the nanofluid as working fluid during both seasons and quite satisfactory by using the water during summer and winter seasons. Overall, proposed system has potential for further development in solar cooling system.