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Journal Articles

Evaluating the Influence of Morphological Features on the Vulnerability of Lipid-Rich Plaques During Stenting

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Jose A. Colmenarez, Pengfei Dong, Juhwan Lee, David L. Wilson, Linxia Gu
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2025, 147(2): 021007.
Paper No: BIO-24-1141
https://doi.org/10.1115/1.4067398
Published Online: January 3, 2025
View Article titled, Evaluating the Influence of Morphological Features on the Vulnerability of Lipid-Rich Plaques During Stenting
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Topics: Sensitivity analysis, Stents, Stress, Rupture
Journal Articles

Modified Centroid of Root Projection Method for Determining the Center of Resistance of a Tooth

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Jianing Wang, Thyagaseely Sheela Premaraj, Sundaralingam Prem Premaraj, Linxia Gu, Pengfei Dong
Journal: Journal of Engineering and Science in Medical Diagnostics and Therapy
Publisher: ASME
Article Type: Research-Article
ASME J of Medical Diagnostics. August 2025, 8(3): 031010.
Paper No: JESMDT-24-1075
https://doi.org/10.1115/1.4066936
Published Online: November 21, 2024
View Article titled, Modified Centroid of Root Projection Method for Determining the Center of Resistance of a Tooth
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Topics: Bone, Carbon reinforced plastics, Displacement, Finite element analysis, Hydrostatics, Stress, Stress concentration, Simulation, Rotation
Journal Articles

Effects of Acid Etching on the Microstructure and Stiffness of Human Teeth

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Yingnan Zhai, Zhenshan Shi, Thyagaseely Premaraj, Sundaralingam Premaraj, Tatiana Karpova, Pengfei Dong, Linxia Gu
Journal: Journal of Engineering and Science in Medical Diagnostics and Therapy
Publisher: ASME
Article Type: Research-Article
ASME J of Medical Diagnostics. August 2025, 8(3): 031005.
Paper No: JESMDT-24-1061
https://doi.org/10.1115/1.4066624
Published Online: October 16, 2024
View Article titled, Effects of Acid Etching on the Microstructure and Stiffness of Human Teeth
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Topics: Atomic force microscopy, Enameling, Etching, Stiffness, Scanning electron microscopy, Rods
Journal Articles

Machine Learning for Early Breast Cancer Detection

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Nure Alam Chowdhury, Lulu Wang, Linxia Gu, Mehmet Kaya
Journal: Journal of Engineering and Science in Medical Diagnostics and Therapy
Publisher: ASME
Article Type: Review Articles
ASME J of Medical Diagnostics. February 2025, 8(1): 010801.
Paper No: JESMDT-24-1017
https://doi.org/10.1115/1.4065756
Published Online: July 26, 2024
View Article titled, Machine Learning for Early Breast Cancer Detection
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Topics: Cancer, Machine learning, Machinery, Magnetic resonance imaging, Ultrasound, Thermography, Mammography, Imaging, Convolutional neural networks
Proceedings Papers

Multiscale Mechanical Characterization of Cornea With AFM, SEM, and Uniaxial Tensile Test

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Yingnan Zhai, Jose A. Colmenarez, Valentina O. Mendoza, Pengfei Dong, Kenia Nunes, Donny Suh, Linxia Gu
Proc. ASME. IMECE2023, Volume 5: Biomedical and Biotechnology, V005T06A010, October 29–November 2, 2023
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2023-113394
https://doi.org/10.1115/IMECE2023-113394
View Paper titled, Multiscale Mechanical Characterization of Cornea With AFM, SEM, and Uniaxial Tensile Test
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Topics: Atomic force microscopy, Cornea
Proceedings Papers

A Finite Element Model for Analyzing the Shear Wave Propagation in Soft Biomaterials

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Jianing Wang, Runze Li, Qifa Zhou, Linxia Gu, Pengfei Dong
Proc. ASME. IMECE2023, Volume 5: Biomedical and Biotechnology, V005T06A051, October 29–November 2, 2023
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2023-114066
https://doi.org/10.1115/IMECE2023-114066
View Paper titled, A Finite Element Model for Analyzing the Shear Wave Propagation in Soft Biomaterials
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Topics: Biomaterials, Elastography, Finite element analysis, Finite element model, Shear waves, Simulation
Proceedings Papers

Damage-Induced Softening of the Sclera: A Pseudo-Elastic Modeling Approach

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Jose A. Colmenarez, Yingnan Zhai, Valentina O. Mendoza, Pengfei Dong, Kenia Nunes, Donny Suh, Linxia Gu
Proc. ASME. IMECE2023, Volume 5: Biomedical and Biotechnology, V005T06A009, October 29–November 2, 2023
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2023-112270
https://doi.org/10.1115/IMECE2023-112270
View Paper titled, Damage-Induced Softening of the Sclera: A Pseudo-Elastic Modeling Approach
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Topics: Biomechanics, Damage, Finite element analysis, Modeling
Proceedings Papers

A Reduced Order Model for Estimation of Fractional Flow Reserve (FFR) in Coronary Artery Disease: Assessing the Impact of Side Branches

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Arber Vila, Mohammad Ahmed, Amirtaha Taebi, Pengfei Dong, Linxia Gu, Peshala Thibbotuwawa Gamage
Proc. ASME. IMECE2023, Volume 5: Biomedical and Biotechnology, V005T06A046, October 29–November 2, 2023
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2023-112632
https://doi.org/10.1115/IMECE2023-112632
View Paper titled, A Reduced Order Model for Estimation of Fractional Flow Reserve (FFR) in Coronary Artery Disease: Assessing the Impact of Side Branches
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Topics: Coronary arteries, Diseases, Flow (Dynamics)
Journal Articles

Modeling of a Hexagonal Microstrip Patch Antenna for Breast Cancer Detection

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Nure Alam Chowdhury, Lulu Wang, Md Shazzadul Islam, Linxia Gu, Mehmet Kaya
Journal: Journal of Engineering and Science in Medical Diagnostics and Therapy
Publisher: ASME
Article Type: Research-Article
ASME J of Medical Diagnostics. August 2024, 7(3): 031007.
Paper No: JESMDT-23-1058
https://doi.org/10.1115/1.4064068
Published Online: December 18, 2023
View Article titled, Modeling of a Hexagonal Microstrip Patch Antenna for Breast Cancer Detection
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Topics: Cancer, Design, Phantoms, Strip transmission lines, Tumors
Journal Articles

Analysis of Shear Wave Propagation in Soft Biomaterials Using a Finite Element Model

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Jianing Wang, Runze Li, Qifa Zhou, Linxia Gu, Pengfei Dong
Journal: Journal of Engineering and Science in Medical Diagnostics and Therapy
Publisher: ASME
Article Type: Research-Article
ASME J of Medical Diagnostics. August 2024, 7(3): 031004.
Paper No: JESMDT-23-1048
https://doi.org/10.1115/1.4063598
Published Online: October 26, 2023
View Article titled, Analysis of Shear Wave Propagation in Soft Biomaterials Using a Finite Element Model
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Topics: Biomaterials, Elastography, Finite element analysis, Phantoms, Shear waves, Simulation, Waves, Finite element model, Displacement, Stiffness
Journal Articles

Damage-Induced Softening of the Sclera: A Pseudo-Elastic Modeling Approach

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Jose A. Colmenarez, Yingnan Zhai, Valentina Ochoa Mendoza, Pengfei Dong, Kenia Nunes, Donny Suh, Linxia Gu
Journal: Journal of Engineering and Science in Medical Diagnostics and Therapy
Publisher: ASME
Article Type: Research-Article
ASME J of Medical Diagnostics. August 2024, 7(3): 031001.
Paper No: JESMDT-23-1049
https://doi.org/10.1115/1.4063467
Published Online: October 9, 2023
View Article titled, Damage-Induced Softening of the Sclera: A Pseudo-Elastic Modeling Approach
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Topics: Damage, Stress, Finite element analysis, Biomechanics, Fittings
Journal Articles

Tissue Growth Model for Maintaining Tensional Homeostasis With Applications to Hypertension and Stented Artery

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Pengfei Dong, Kenia Nunes, Linxia Gu
Journal: Journal of Engineering and Science in Medical Diagnostics and Therapy
Publisher: ASME
Article Type: Research-Article
ASME J of Medical Diagnostics. November 2023, 6(4): 041004.
Paper No: JESMDT-23-1009
https://doi.org/10.1115/1.4062387
Published Online: May 15, 2023
View Article titled, Tissue Growth Model for Maintaining Tensional Homeostasis With Applications to Hypertension and Stented Artery
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Topics: Biological tissues, Stents, Stress, Deformation, Stress concentration
Proceedings Papers

Evaluation of 3D-Printed Gel Using a Flat-Ended Square Indenter

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Ana Isabel Delgado, Pengfei Dong, Linxia Gu
Proc. ASME. IMECE2022, Volume 4: Biomedical and Biotechnology; Design, Systems, and Complexity, V004T05A027, October 30–November 3, 2022
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2022-95004
https://doi.org/10.1115/IMECE2022-95004
View Paper titled, Evaluation of 3D-Printed Gel Using a Flat-Ended Square Indenter
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Topics: Additive manufacturing, Stiffness, Dimensions, Biomaterials, Displacement, Finite element analysis, Mechanical properties, Microscale devices
Journal Articles

Eye Protection for Mitigating Soccer-Related Ocular Injuries: A Finite Element Approach

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Yasin Shokrollahi, Pengfei Dong, Matthew Lam, Donny W. Suh, Linxia Gu
Journal: Journal of Engineering and Science in Medical Diagnostics and Therapy
Publisher: ASME
Article Type: Research-Article
ASME J of Medical Diagnostics. November 2022, 5(4): 041003.
Paper No: JESMDT-21-1061
https://doi.org/10.1115/1.4054428
Published Online: June 2, 2022
View Article titled, Eye Protection for Mitigating Soccer-Related Ocular Injuries: A Finite Element Approach
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Topics: Eye protection, Wounds, Stress, Pressure
Proceedings Papers

Mechanical Characterization of Calcificaiton in Diseased Coronary Artery with Atomic Force Microscope

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Ana Delgado, Pengfei Dong, Mahyar Sameti, Vladislav N. Zimin, Juhwan Lee, Yazan Gharaibeh, Hiram G. Bezerra, David Wilson, Christopher Bashur, Linxia Gu
Proc. ASME. DMD2022, 2022 Design of Medical Devices Conference, V001T01A004, April 11–14, 2022
Publisher: American Society of Mechanical Engineers
Paper No: DMD2022-1055
https://doi.org/10.1115/DMD2022-1055
View Paper titled, Mechanical Characterization of Calcificaiton in Diseased Coronary Artery with Atomic Force Microscope
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Topics: Atomic force microscopy, Coronary arteries
Proceedings Papers

Strain-Based Degradation Model With Application to Poly-L-Lactide Acid (PLLA) Artery Stent

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Shengmao Lin, Pengfei Dong, Linxia Gu
Proc. ASME. IMECE2021, Volume 5: Biomedical and Biotechnology, V005T05A007, November 1–5, 2021
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2021-72395
https://doi.org/10.1115/IMECE2021-72395
View Paper titled, Strain-Based Degradation Model With Application to Poly-L-Lactide Acid (PLLA) Artery Stent
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Topics: Finite element methods, Stents
Journal Articles

Optical Coherence Tomography-Based Modeling of Stent Deployment in Heavily Calcified Coronary Lesion

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Pengfei Dong, Hozhabr Mozafari, David Prabhu, Hiram G. Bezerra, David L. Wilson, Linxia Gu
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. May 2020, 142(5): 051012.
Paper No: BIO-19-1293
https://doi.org/10.1115/1.4045285
Published Online: January 20, 2020
View Article titled, Optical Coherence Tomography-Based Modeling of Stent Deployment in Heavily Calcified Coronary Lesion
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Topics: Biological tissues, Coherence (Optics), Stents, Stress, Cross section (Physics), Modeling, Struts (Engineering)
Journal Articles

Indirect Traumatic Optic Neuropathy Induced by Primary Blast: A Fluid–Structure Interaction Study

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Junfei Tong, Sachin Kedar, Deepta Ghate, Linxia Gu
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2019, 141(10): 101011.
Paper No: BIO-18-1504
https://doi.org/10.1115/1.4043668
Published Online: July 29, 2019
View Article titled, Indirect Traumatic Optic Neuropathy Induced by Primary Blast: A Fluid–Structure Interaction Study
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Topics: Cerebrospinal fluid, Fluid structure interaction, Pressure, Waves, Wounds, Materials properties, Biological tissues, Damage, Transients (Dynamics)
Proceedings Papers

The Influence of Primary Blast Wave on the Posterior Part of the Eyeball

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Junfei Tong, Linxia Gu
Proc. ASME. IMECE2018, Volume 3: Biomedical and Biotechnology Engineering, V003T04A058, November 9–15, 2018
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2018-88113
https://doi.org/10.1115/IMECE2018-88113
View Paper titled, The Influence of Primary Blast Wave on the Posterior Part of the Eyeball
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Topics: Waves, Wounds, Military systems, Cerebrospinal fluid, Computation, Damage, Engineering simulation, Improvised explosive devices, Physiology, Rupture
Proceedings Papers

Degradation Modeling of Bioabsorbable Polymer Stent

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Pengfei Dong, Longzhen Wang, Linxia Gu
Proc. ASME. IMECE2018, Volume 3: Biomedical and Biotechnology Engineering, V003T04A059, November 9–15, 2018
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2018-88116
https://doi.org/10.1115/IMECE2018-88116
View Paper titled, Degradation Modeling of Bioabsorbable Polymer Stent
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Topics: Biocompatible polymers, Modeling, Stents, Young's modulus, Failure, Finite element analysis, Materials properties, Switches