The operating environment of polyethylene (PE) gas pipeline is complex and changeable. In the process of pipeline design, construction and operation, there are many fuzzy factors inducing pipeline accidents. In the paper, the fuzzy factors causing pipeline accidents were studied and analyzed, and the risk evaluation factors of PE gas pipeline were determined. According to the theory of fuzzy comprehensive evaluation, the mathematical model of fuzzy comprehensive evaluation for PE pipeline was established. In order to pursue as much accurate results of assessment as possible, the fuzzy analytic hierarchy process was used to determine the weight of each index. The safety evaluation grade of the pipeline was given by using the risk matrix method. And then the evaluation system software of PE gas pipeline risk assessment was developed. The software has been used in the risk inspection of PE gas pipeline, which provides the basis for the risk management of the pipeline.