Heat pipe characteristics are linked to the surface properties of the diabatic surfaces, and, in the evaporator, surface properties influence both the onset boiling temperature (T ONB ) and the critical heat flux (CHF). In this work, the effect of surface wettability in pool boiling heat transfer is studied in order to understand if there could be a path to increment heat pipe thermal performance. This work analyzes the effects of surface wettability on boiling (tested fluid is pure water) and proposes a new super-hydrophobic polymeric coating (De Coninck et al., 2017, “Omniphobic Surface Coatings,” Patent No. WO/2017/220591), which can have a very important effect in improving the heat pipe start-up power load and increasing the thermal performance of heat pipes when the flux is lower than the critical heat flux. The polymeric coating is able to reduce the T ONB (−11% from 117 °C to about 104 °C) compared with the uncoated surfaces, as it inhibits the formation of a vapor film on the solid–liquid interface, avoiding CHF conditions up to maximum wall temperature (125 °C). This is realized by the creation of a heterogeneous surface with superhydrophobic surface (SHS) zones dispersed on top of a hydrophilic surface (stainless steel surface). The proposed coating has an outstanding thermal resistance: No degradation of SH properties of the coating has been observed after more than 500 thermal cycles.