The plastic damage caused by multiple dynamic loading and its influence on the ductility and toughness of 3.5% Ni steel (SA203E) and C steel (SA516M) were examined for the discussion of integrity design of detonation chambers. V-notched specimens and hourglass specimens were welded on the 1/7-scale model of a 1-ton explosive class detonation chamber and subjected to 30 detonation shots. It has been indicated that 30 detonation shots caused prestrain in the specimens. The ductility was reduced by the prestrain. The Charpy impact toughness was affected as well in a lower temperature. It has been noted that the damage is developed with fatigue crack growth at the notch root of the V-notched specimen.

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