Hyperthyroid and thyroid carcinoma patients treated with radioactive 131I (RAI) are a potential source of external and internal exposure to members of the public, to medical staff and especially to family members, who are in close contact with these patients. The relationship between radiation dose rates and various clinical parameters, including gender, age, thyroid size and weight, and iodine uptake, was assessed. Dose rates were measured on eight patients with thyroid carcinoma after total or subtotal thyroidectomy and on six patients with hyperthyroidism. All measurements were taken at 1 m from the patient on two levels—anterior to the neck and body center. Dose rates were measured at three or four times—at the time of RAI administration, and after 24 h, 48 h, and 168 h. Based on these measurements, retention curves were obtained. The effective half-life was derived by fitting an exponential equation and was estimated to be 12.8 h.
A Study of the External Exposure Decay Curves as a Function of Several Clinical Parameters for Patients Treated With Therapeutic 131I
Manuscript received August 30, 2016; final manuscript received April 2, 2017; published online May 25, 2017. Assoc. Editor: Jean Koch.
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Ginzburg, D., Lantsberg, S., and Faermann, S. (May 25, 2017). "A Study of the External Exposure Decay Curves as a Function of Several Clinical Parameters for Patients Treated With Therapeutic 131I." ASME. ASME J of Nuclear Rad Sci. July 2017; 3(3): 030906. https://doi.org/10.1115/1.4036433
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