Abstract

A prolonged increase in intra-abdominal pressure (IAP) is life-threatening, yet commonly seen in intensive care units (ICUs). Despite this, existing clinically accepted IAP measurement techniques are invasive and not inter-rater reliable. As such, it is the effort of this research to develop a direct, noninvasive, handheld tool to measure internal pressures in pressurized, physiological vessels. The novel device uses a localized known pressure (namely, aspiration) to measure resulting tissue deformation, from which internal pressures can be divulged considering the extended Hencky solution. Two male participants were tested with the device to confirm feasibility of the theoretical device function for IAP measurement. Participants' Young's moduli of the abdominal wall were calculated with measured IAP values. Results were consistent with participant body mass indices and overall health. Average measured IAP was 0.42 kPa and 0.46 kPa at supine and inclined positions, respectively. Average measured abdominal wall elasticity was 14.91 kPa and 23.09 kPa at supine and inclined positions, respectively. These preliminary findings suggest the potential use of the device described herein as a measurement system for pressurized vessels, whereas the system will be tested on a larger sample size before recommending clinical use.

References

References
1.
Malbrain
,
M. L. N. G.
,
Roberts
,
D. J.
,
De Laet
,
I.
,
De Waele
,
J. J.
,
Sugrue
,
M.
,
Schachtrupp
,
A.
,
Duchesne
,
J.
,
Van Ramshorst
,
G.
,
De Keulenaer
,
B.
,
Kirkpatrick
,
A. W.
,
Ahmadi-Noorbakhsh
,
S.
,
Mulier
,
J.
,
Ivatury
,
R.
,
Pracca
,
F.
,
Wise
,
R.
, and
Pelosi
,
P.
,
2014
, “
The Role of Abdominal Compliance, the Neglected Parameter in Critically Ill Patients—A Consensus Review of 16. Part 1: Definitions and Pathophysiology
,”
Anesthesiol. Intensive Ther.
,
46
(
5
), pp.
392
405
.10.5603/AIT.2014.0062
2.
Malbrain
,
M. L. N. G.
,
Cheatham
,
M. L.
,
Kirkpatrick
,
A.
,
Sugrue
,
M.
,
Parr
,
M.
,
De Waele
,
J.
,
Balogh
,
Z.
,
Leppäniemi
,
A.
,
Olvera
,
C.
,
Ivatury
,
R.
,
D'Amours
,
S.
,
Wendon
,
J.
,
Hillman
,
K.
,
Johansson
,
K.
,
Kolkman
,
K.
, and
Wilmer
,
A.
,
2006
, “
Results From the International Conference of Experts on Intra-Abdominal Hypertension and Abdominal Compartment Syndrome—I: Definitions
,”
Intensive Care Med.
,
32
(
11
), pp.
1722
1732
.10.1007/s00134-006-0349-5
3.
Papavramidis
,
T.
,
Marinis
,
A.
,
Pliakos
,
I.
,
Kesisoglou
,
I.
, and
Papavramidou
,
N.
,
2011
, “
Abdominal Compartment Syndrome—Intra-Abdominal Hypertension: Defining, Diagnosing, and Managing
,”
J. Emerg. Trauma Shock
,
4
(
2
), pp.
279
291
.10.4103/0974-2700.82224
4.
Roberts
,
D.
,
De Waele
,
J.
,
Kirkpatrick
,
A.
, and
Malbrain
,
M.
,
2016
, “
Intra-Abdominal Hypertension and the Abdominal Compartment Syndrome
,”
Surg. Intensive Care Med.
,
39
(
7
), pp.
1
644
.10.1097/MCC.0000000000000289
5.
Blaser
,
A.
,
Regli
,
A.
,
De Keulenaer
,
B.
,
Kimball
,
E.
,
Starkopf
,
L.
,
Davis
,
W.
,
Greiffenstein
,
P.
, and
Starkopf
,
J.
,
2019
, “
Incidence, Risk Factors, and Outcomes of Intra-Abdominal Hypertension in Critically Ill Patients-A Prospective Multicenter Study (IROI Study)
,”
Crit. Care Med.
,
47
(
4
), pp.
535
542
.10.1097/CCM.0000000000003623
6.
Milanesi
,
R.
, and
Caregnato
,
R.
,
2016
, “
Intra-Abdominal Pressure: An Integrative Review
,”
Einstein
,
14
(
3
), pp.
423
430
.10.1590/S1679-45082016RW3088
7.
El-Monajjed
,
K.
, and
Driscoll
,
M.
,
2020
, “
A Finite Element Analysis of the Intra-Abdominal Pressure and Paraspinal Muscle Compartment Pressure Interaction Through the Thoracolumbar Fascia
,”
Comput. Methods Biomech. Biomed. Eng.
, 23(10), pp.
1
12
.10.1080/10255842.2020.1752682
8.
Hodges
,
P.
,
Eriksson
,
A.
,
Shirley
,
D.
, and
Gandevia
,
S.
,
2005
, “
Intra-Abdominal Pressure Increases Stiffness of the Lumbar Spine
,”
J. Biomech.
,
38
(
9
), pp.
1873
1880
.10.1016/j.jbiomech.2004.08.016
9.
Cheatham
,
M. L.
,
Malbrain
,
M. L. N. G.
,
Kirkpatrick
,
A.
,
Sugrue
,
M.
,
Parr
,
M.
,
De Waele
,
J.
,
Balogh
,
Z.
,
Leppäniemi
,
A.
,
Olvera
,
C.
,
Ivatury
,
R.
,
D'Amours
,
S.
,
Wendon
,
J.
,
Hillman
,
K.
, and
Wilmer
,
A.
,
2007
, “
Results From the International Conference of Experts on Intra-Abdominal Hypertension and Abdominal Compartment Syndrome—II: Recommendations
,”
Intensive Care Med.
,
33
(
6
), pp.
951
962
.10.1007/s00134-007-0592-4
10.
Malbrain
,
M.
,
2004
, “
Different Techniques to Measure Intra-Abdominal Pressure (IAP): Time for a Critical Re-Appraisal
,”
Intensive Care Med.
,
30
(
3
), pp.
357
371
.10.1007/s00134-003-2107-2
11.
Otto
,
J.
,
Kaemmer
,
D.
,
Binnebosel
,
M.
,
Jansen
,
M.
,
Dembinski
,
R.
,
Schumpelick
,
V.
, and
Schachtrupp
,
A.
,
2009
, “
Direct Intra-Abdominal Pressure Monitoring Via Piezoresistive Pressure Measurement: A Technical Note
,”
BMC Surg.
,
9
(
1
), pp.
1
5
.10.1186/1471-2482-9-5
12.
Pracca
,
F.
,
Biestro
,
A.
,
Moraes
,
L.
,
Puppo
,
C.
,
Calvo
,
S.
,
Gorrasi
,
J.
, and
Cancela
,
M.
,
2007
, “
Direct Measurement of Intra-Abdominal Pressure With a Solid Microtransducer
,”
J. Clin. Monitor. Comput.
,
21
(
3
), pp.
167
170
.10.1007/s10877-007-9071-2
13.
Al-Abassi
,
A.
,
Al Saadi
,
A.
, and
Ahmed
,
F.
,
2018
, “
Is Intra-Bladder Pressure Measurement a Reliable Indicator for Raised Intra-Abdominal Pressure? a Prospective Comparative Study
,”
BMC Anesthes.
,
18
(
69
), pp.
1
9
.10.1186/s12871-018-0539-z
14.
Chen
,
Y.
,
Yan
,
S.
,
Chen
,
Y.
,
Zhuang
,
Y.
,
Wei
,
Z.
,
Zhou
,
S.
, and
Peng
,
H.
,
2015
, “
Noninvasive Monitoring of Intra-Abdominal Pressure by Measuring Abdominal Wall Tension
,”
World J. Emerg. Med.
,
6
(
2
), pp.
137
141
.10.5847/wjem.j.1920-8642.2015.02.009
15.
Bloch
,
A.
,
Glas
,
M.
,
Kohler
,
A.
,
Baumann
,
U.
, and
Jakob
,
S.
,
2018
, “
Noninvasive Assessment of Intra-Abdominal Pressure Using Ultrasound-Guided Tonometry: A Proof-of-Concept Study
,”
Shock
,
50
(
6
), pp.
684
688
.10.1097/SHK.0000000000001085
16.
Johnson
,
P.
,
Rosenbluth
,
E.
,
Nygaard
,
I.
,
Parikh
,
M.
, and
Hitchcock
,
R.
,
2009
, “
Development of a Novel Intra-Vaginal Transducer With Improved Dynamic Response
,”
Biomed. Microdevice
,
11
(
6
), pp.
1213
1221
.10.1007/s10544-009-9339-z
17.
Coleman
,
T.
,
Thomsen
,
J.
,
Maass
,
S.
,
Hsu
,
Y.
,
Nygaard
,
I.
, and
Hitchcock
,
R.
,
2012
, “
Development of a Wireless Intra-Vaginal Transducer for Monitoring Intra-Abdominal Pressure in Women
,”
Biomed. Microdevice
,
14
(
2
), pp.
347
355
.10.1007/s10544-011-9611-x
18.
Van Ramshorst
,
G.
,
Lange
,
J.
,
Goossens
,
R.
,
Agudelo
,
N.
,
Kleinrensink
,
G.
,
Verwaal
,
M.
,
Flipsen
,
S.
,
Hop
,
W.
,
Wauben
,
L.
, and
Jeekel
,
J.
,
2008
, “
Non-Invasive Measurement of Intra-Abdominal Pressure: A Preliminary Study
,”
Physiol. Meas.
,
29
(
8
), pp.
N41
N47
.10.1088/0967-3334/29/8/N01
19.
Primiano
,
F.
,
1982
, “
Theoretical Analysis of Chest Wall Mechanics
,”
J. Biomech.
,
15
(
12
), pp.
919
931
.10.1016/0021-9290(82)90010-0
20.
David
,
M.
,
Raviv
,
A.
,
Peretz
,
A.
,
Berkovich
,
U.
, and
Pracca
,
F.
,
2018
, “
Towards a Continuous Noninvasive Assessment of Intra-Abdominal Pressure Based on Bioimpedance and Microwave Reflectometry: A Pilot Run on a Porcine Model
,”
Biomed. Signal Process. Control
,
44
, pp.
96
100
.10.1016/j.bspc.2018.04.003
21.
Fichter
,
W.
,
1997
, “
Some Solutions for the Large Deflections of Uniformly Loaded Circular Membranes
,” NASA, Washington, DC, Paper No.
3658
.https://ntrs.nasa.gov/citations/19970023537
22.
Sun
,
J.
,
Lian
,
Y.
,
Li
,
Y.
,
He
,
X.
, and
Zheng
,
Z.
,
2015
, “
Closed-Form Solution of Elastic Circular Membrane With Initial Stress Under Uniformly-Distributed Loads: Extended Hencky Solution
,”
ZAMM Z. Angew. Math. Mech.
,
95
(
11
), pp.
1335
1341
.10.1002/zamm.201400032
23.
Muvdi
,
B.
, and
McNabb
,
J.
,
1991
,
Engineering Mechanics of Materials
,
Springer
,
New York
, Chap.
13
.
24.
Flint
,
A.
,
Rexrode
,
K.
,
Hu
,
F.
,
Glynn
,
R.
,
Caspard
,
H.
,
Manson
,
J.
,
Willett
,
W.
, and
Rimm
,
E.
,
2010
, “
Body Mass Index, Waist Circumference, and Risk of Coronary Heart Disease: A Prospective Study Among Men and Women
,”
Obes. Res. Clin. Pract.
,
4
(
3
), pp.
171
181
.10.1016/j.orcp.2010.01.001
25.
Song
,
C.
,
Alijani
,
A.
,
Frank
,
T.
,
Hanna
,
G.
, and
Cuschieri
,
A.
,
2006
, “
Mechanical Properties of the Human Abdominal Wall Measured In Vivo During Insufflation for Laparoscopic Surgery
,”
Surg. Endoscopy Other Interventional Tech.
,
20
(
6
), pp.
987
990
.10.1007/s00464-005-0676-6
26.
Tran
,
D.
,
Podwojewski
,
F.
,
Beillas
,
P.
,
Ottenio
,
M.
,
Voirin
,
D.
,
Turquier
,
F.
, and
Mitton
,
D.
,
2016
, “
Abdominal Wall Muscle Elasticity and Abdomen Local Stiffness on Healthy Volunteers During Various Physiological Activities
,”
J. Mech. Behav. Biomed. Mater.
,
60
, pp.
451
459
.10.1016/j.jmbbm.2016.03.001
27.
Miller
,
R.
,
Kolipaka
,
A.
,
Nash
,
M.
, and
Young
,
A.
,
2018
, “
Relative Identifiability of Anisotropic Properties From Magnetic Resonance Elastography
,”
NMR Biomed.
,
31
, pp.
1
12
.10.1002/nbm.3848
28.
Aquina
,
C.
,
Iannuzzi
,
J.
,
Probst
,
C.
,
Kelly
,
K.
,
Noyes
,
K.
,
Fleming
,
F.
, and
Monson
,
J.
,
2014
, “
Parastomal Hernia: A Growing Problem With New Solutions
,”
Dig. Surg.
,
31
(
4–5
), pp.
366
376
.10.1159/000369279
29.
Konerding
,
M.
,
Bohn
,
M.
,
Wolloscheck
,
T.
,
Batke
,
B.
,
Holste
,
J.
,
Wohlert
,
S.
,
Trzewik
,
J.
,
Forstemann
,
T.
, and
Hartung
,
C.
,
2011
, “
Maximum Forces Acting on the Abdominal Wall: Experimental Validation of a Theoretical Modeling in a Human Cadaver Study
,”
Med. Eng. Phys.
,
33
(
6
), pp.
789
792
.10.1016/j.medengphy.2011.01.010
30.
Cheatham
,
M.
,
De Waele
,
J.
,
De Laet
,
I.
,
De Keulenaer
,
B.
,
Widder
,
S.
,
Kirkpatrick
,
A.
,
Cresswell
,
A.
,
Malbrain
,
M.
,
Bodnar
,
Z.
,
Mejia-Mantilla
,
J.
,
Reis
,
R.
,
Parr
,
M.
,
Schulze
,
R.
, and
Puig
,
S.
,
2009
, “
The Impact of Body Position on Intra-Abdominal Pressure Measurement: A Multicenter Analysis
,”
Crit. Care Med.
,
37
(
7
), pp.
2187
2190
.10.1097/CCM.0b013e3181a021fa
31.
Hayes
,
W.
,
Keer
,
L.
,
Herrmann
,
G.
, and
Mockros
,
L.
,
1972
, “
A Mathematical Analysis for Indentation Tests of Articular Cartilage
,”
J. Biomech.
,
5
(
5
), pp.
541
551
.10.1016/0021-9290(72)90010-3
32.
Zhang
,
M.
,
Zheng
,
Y.
, and
Mak
,
A.
,
1997
, “
Estimating the Effective Young's Modulus of Soft Tissues From Indentation Tests—Nonlinear Finite Element Analysis of Effects of Friction and Large Deformation
,”
Med. Eng. Phys.
,
19
(
6
), pp.
512
517
.10.1016/S1350-4533(97)00017-9
You do not currently have access to this content.