Abstract

Significant research has been done in the past decade for development of MRI guided needle guide systems for prostate intervention. Most of these systems have been restricted to application in the lab environment with lack of progress towards clinical application. Bulky and complex designs can be attributed to this practice. These systems also demand complex technical setup and usage procedures, which require extra technical personnel during the intervention in addition to specialized training for physicians. Moreover, 'device-to-image' registration, essential for accurate and precise targeting, further complicates the overall process while increasing total time for intervention. In order to address these limitations, a simplified, MRI guided, transperineal prostate biopsy needle guide was designed and developed for rapid adoption into the clinical environment. This system design does not require any special intraprocedural technical expertise or dedicated training. Also, to simplify and shorten total procedure time, the needle guide uses the unique concept of 'fixed coordinate device' eliminating the need for any 'device-to-image' registration making it clinically friendly. To verify the needle guide design along with the registration free feature, image quality tests and agar phantom based targeting experiments were performed under the guidance of 3T MRI scanner. The results show that a simplified intervention device without the need of 'device-to-image' registration is technically feasible.

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