Stents have revolutionized the treatment of arterial disease. Acting as a supporting scaffold, these small mesh devices are now routinely inserted into arteries where the blood flow has become dangerously restricted. While coronary artery stenting is now relatively mature, significant scientific and technological challenges still remain. Overall, however, the revolutionary success of coronary artery stenting has led to the emergence of stenting technology for the carotid, neural, and peripheral vasculature. And the adaptability of the stent concept has opened horizons beyond the vasculature, with stent technology now being developed for, amongst others, pulmonary, gastro-intestinal, and structural heart applications (e.g., transcatheter aortic valve implantation stents).

In relation to coronary stents, one of the most fertile technological growth areas is biodegradable stents; here there is the possibility to generate stents that will break down in the body once the initial necessary scaffolding period is past (6–12 months...

References

References
1.
Grogan
,
J. A.
,
O'Brien
,
B. J.
,
Leen
,
S. B.
, and
McHugh
,
P. E.
,
2011
, “
A Corrosion Model for Bioabsorbable Metallic Stents
,”
Acta Biomater.
,
7
(
9
), pp.
3523
3533
.10.1016/j.actbio.2011.05.032
2.
Grogan
,
J. A.
,
Leen
,
S. B.
, and
McHugh
,
P. E.
,
2013
, “
Optimizing the Design of a Bioabsorbable Metal Stent Using Computer Simulation Methods
,”
Biomaterials
,
34
(
33
), pp.
8049
8060
.10.1016/j.biomaterials.2013.07.010
3.
Patel
,
N.
, and
Banning
,
A. P.
,
2013
, “
Bioabsorbable Scaffolds for the Treatment of Obstructive Coronary Artery Disease: The Next Revolution in Coronary Intervention?
Heart
,
99
(
17
), pp.
1236
1243
.10.1136/heartjnl-2012-303346
4.
Haude
,
M.
,
Erbel
,
R.
,
Erne
,
P.
,
Verheye
,
S.
,
Degen
,
H.
,
Bose
,
D.
,
Vermeersch
,
P.
,
Wijnbergen
,
I.
,
Weissman
,
N.
,
Prati
,
F.
,
Waksman
,
R.
, and
Koolen
,
J.
,
2013
, “
Safety and Performance of the Drug-Eluting Metal Scaffold (DREAMS) in Patients With De-Novo Coronary Lesions: 12 Month Results of the Prospective, Multicentre, First-In-Man BIOSOLVE-1 Trial
,”
Lancet
,
381
(
9869
), pp.
836
844
.10.1016/S0140-6736(12)61765-6
5.
Shirazi
,
R. N.
,
Aldabbagh
,
F.
,
Erxleben
,
A.
,
Rochev
,
Y.
, and
McHugh
,
P.
,
2014
, “
Nanomechanical Properties of Poly(Lactic-Co-Glycolic) Acid Film During Degradation
,”
Acta Biomater.
,
10
(
11
), pp.
4695
4703
.10.1016/j.actbio.2014.08.004
6.
Conway
,
C.
,
Sharif
,
F.
,
McGarry
,
J.
, and
McHugh
,
P.
,
2012
, “
A Computational Test-Bed to Assess Coronary Stent Implantation Mechanics Using a Population-Specific Approach
,”
Cardiovasc. Eng. Technol.
,
3
(
4
), pp.
374
387
.10.1007/s13239-012-0104-8
7.
Conway
,
C.
,
McGarry
,
J. P.
, and
McHugh
,
P. E.
,
2014
, “
Modelling of Atherosclerotic Plaque for Use in a Computational Test-Bed for Stent Angioplasty
,”
Ann. Biomed. Eng.
,
42
(
12
), pp.
2425
2439
.10.1007/s10439-014-1107-4
8.
Lally
,
C.
,
2004
, “
An Investigation Into the Influence of Cardiovascular Stent Design on the Development of Restenosis Using the Finite Element Method
,” Ph.D. thesis, Trinity College Dublin, Dublin, Ireland.
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