The esophagus (muscular tube that conveys food from the oral cavity to the stomach through the process of peristalsis) is a vital organ that plays a critical role in the digestive system. Temporary or permanent injury of the esophagus can have severe clinical implications. Any form of physical injury or loss of function will result in lower quality of life. Esophageal injury can happen in many ways, for example, esophageal cancer, gastroesophageal reflux disease, Barrett's esophagus, achalasia, tylosis, during interventional procedures (treatment of cardiac arrhythmias), and use of tobacco and alcohol to name a few. Though chemotherapy remains the first line of treatment, in severe cases, esophagectomy can be inevitable. There have been numerous efforts in researching xenografts and developing artificial esophagus that possess all the necessary qualities of native esophagus including peristalsis [1]; however, this still remains an active area of investigation....

References

References
1.
Watanabe
,
M.
,
Sekine
,
K.
,
Hori
,
Y.
,
Shiraishi
,
Y.
,
Maeda
,
T.
,
Honma
,
D.
,
Miyata
,
G.
,
Saijo
,
Y.
, and
Yambe
,
T.
,
2005
, “
Artificial Esophagus With Peristaltic Movement
,”
ASAIO J.
,
51
(
2
), pp.
158
161
.10.1097/01.MAT.0000154644.44891.F1
2.
Singal
,
A.
,
Soule
,
C. L.
,
Ballard
,
J. R.
,
Cressman
,
E. N.
, and
Iaizzo
,
P. A.
,
2014
, “
Physiological Tissue Response to Various Ablative Modalities
,”
ASME J. Med. Devices
,
8
(
2
), p.
020906
.10.1115/1.4027005
3.
Meyer
,
G. W.
,
Austin
,
R. M.
,
Brady
,
C. E.
, III
, and
Castell
,
D. O.
,
1986
, “
Muscle Anatomy of the Human Esophagus
,”
J. Clin. Gastroenterol.
,
8
(
2
), pp.
131
134
.10.1097/00004836-198604000-00005
4.
Yazaki
,
E1.
, and
Sifrim
,
D.
,
2012
, “
Anatomy and Physiology of the Esophageal Body
,”
Dis. Esophagus
,
25
(
4
), pp.
292
298
.10.1111/j.1442-2050.2011.01180.x
You do not currently have access to this content.