Reactive hyperemia (RH) is characterized by temporary increase in blood flow which occurs in a blood vessel following a brief period of ischemia. Following ischemia, there is a shortage of oxygen bioavailability and a build-up of metabolic waste which must be replenished to restore normal function [1]. An increased blood flow, an increased vessel diameter (cross-sectional area) and increased pulsatility are all characteristic normal physiological responses postischemia. The vasodilation postischemia is caused by release of nitric oxide into the blood stream [2]. Over time, the blood flow returns to baseline levels. Endothelial dysfunction (dysfunction of the inner lining of blood vessels), which is commonly associated with reduced nitric oxide levels in the blood stream, is a sign of cardiovascular disease and is a predictor of unsatisfactory clinical results. Peripheral arterial tonometry (PAT) signals from patient's finger have been used in clinical...

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