Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Predictors of CVD risk include arterial stiffness, autonomic imbalance, and hypertension [1]; all of which can be measured through a variety of invasive and noninvasive techniques. Central aortic pressures and associated waveforms like the ones measured using an intra-aortic balloon pump (IABP) convey important information regarding the hemodynamic status of the patient; however, these measurements are invasive in nature and require physician intervention. Peripheral arterial tonometry (PAT) signals have been used as a noninvasive medium for clinical assessment of cardiovascular performance. The test involves measurement of blood flow and pulsatility in the fingertips. Although PAT signals differ substantially from central pressures, they may be mathematically correlated and analyzed by applying digital signal processing (DSP) techniques to extract key clinical signatures of interest. We performed comparative assessment between invasive central aortic pressure...

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