Chronic pain is a significant public health problem throughout the world. In the United States alone, chronic pain accounts for an estimated $61 billion a year in lost work productivity and is the leading cause of disability and reduced quality of life in the working population. Treatment of pain is therefore an important and active area of research. For each new treatment modality or drug developed, quantitative evaluation is necessary to judge its efficacy and optimal target population. Quantitative Sensory Testing (QST) provides a standardized and quantifiable methodology to study pain sensitivity in humans. A QST protocol describes a series of noxious and nonnoxious stimuli (e.g., heat, pressure, or electrical) delivered to a patient, and a semi-objective method for the patient to rate their perception of each stimulus. Using this information, clinicians are able estimate the level of a patient’s pain...

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