A portable transcranial magnetic stimulation (TMS) prototype was designed and constructed for use in clinical trials to manage the pain associated with migraine with aura. In this system, a half-sinusoid (optionally a full-sine) TMS pulse is delivered into a circular coil. The pulse triggering is controlled by a switch in the coil handle. The pulse intensity and polarity are adjustable. Measured pulse parameters (period , maximum magnetic field at coil center ) corresponded to expected values and were in the range described for commercially available TMS apparatus. The maximum current density, computed 3 cm below the coil using a simple model of brain anatomy, was approximately 1.9 times the motor threshold, thus ensuring a sufficient margin for reaching the neuronal threshold in the target area.
Design and Construction of a Portable Transcranial Magnetic Stimulation (TMS) Apparatus for Migraine Treatment
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Charlet de Sauvage, R., Beuter, A., Lagroye, I., and Veyret, B. (February 4, 2010). "Design and Construction of a Portable Transcranial Magnetic Stimulation (TMS) Apparatus for Migraine Treatment." ASME. J. Med. Devices. March 2010; 4(1): 015002. https://doi.org/10.1115/1.4000616
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