Abstract
Warming up blood and intravenous (IV) fluids is crucial to saving lives under certain circumstances as it may prevent hypothermia during the transfusion or infusion process. Several blood and IV fluids warming methods have been developed and studied over the past few decades. Such warming methods range from devices that use electrical energy (external or internal, i.e., using battery packs) to technologies that use chemical energy to generate heat. Additionally, improvised warming methods such as exposure to body heat are often used in lieu of electrical and nonelectrical warmers, especially in harsh and demanding environments such as in combat. The performance and efficacy of the various warming methods currently available vary greatly and a one-size-fits-all solution appears to be nonexistent. This paper aims to provide a comprehensive review of the performance studies conducted on blood and IV fluids warming methods over the past few decades.
References
1.
Gentilello
, L. M.
, and Rifley
, W. J.
, 1991
, “Continuous Arteriovenous Rewarming: Report of A New Technique for Treating Hypothermia
,” J. Trauma
, 31
(8
), pp. 1151
–1154
.10.1097/00005373-199108000-000152.
National Collaborating Centre for Nursing and Supportive Care (UK)
, 2008
, “Clinical Practice Guideline: The Management of Inadvertent Perioperative Hypothermia in Adults
,” Royal College of Nursing (UK), National Collaborating Centre for Nursing and Supportive Care (UK), National Institute for Clinical Excellence (NICE), accessed Mar. 31, 2024, https://www.ncbi.nlm.nih.gov/books/NBK53797/pdf/Bookshelf_NBK53797.pdf3.
Russell
, W. J.
, 1974
, “A Review of Blood Warmers For Massive Transfusion
,” Anaesth. Intensive Care
, 2
(2
), pp. 109
–130
.10.1177/0310057X74002002024.
Gentilello
, L. M.
, Cortes
, V.
, Moujaes
, S.
, Viamonte
, M.
, Malinin
, T. L.
, Ho
, C. H.
, and Gomez
, G. A.
, 1990
, “Continuous Arteriovenous Rewarming: Experimental Results and Thermodynamic Model Simulation of Treatment for Hypothermia
,” J. Trauma
, 30
(12
), pp. 1436
–1449
.10.1097/00005373-199012000-000025.
Mendlowitz
, M.
, 1948
, “The Specific Heat of Human Blood
,” Science
, 107
(2769
), pp. 97
–98
.10.1126/science.107.2769.976.
Smith
, C.
, and Wagner
, K.
, 2008
, “Principles of Fluid and Blood Warming in Trauma
,” Int. Trauma Care (ITACCS)
, 19
, pp. 71
–79
.https://www.semanticscholar.org/paper/Principles-of-Fluid-and-Blood-Warming-in-Trauma-Smith-Wagner/3d229b05d2af01097d78fab27520a1b66accf0677.
Smith
, C. E.
, and Soreide
, E.
, 2005
, “Hypothermia in Trauma Victims
,” Am. Soc. Anesthesiol.' Newsl.
, 69
(11
), pp. 17
–30
.https://pubs.asahq.org/monitor/articleabstract/69/11/17/1311/Hypothermia-in-Trauma-Victims8.
Danzl
, D. F.
, and Pozos
, R. S.
, 1994
, “Accidental Hypothermia
,” New Engl. J. Med.
, 331
(26
), pp. 1756
–1760
.10.1056/NEJM1994122933126079.
Lenhardt
, R.
, Marker
, E.
, Goll
, V.
, Tschernich
, H.
, Kurz
, A.
, Sessler
, D. I.
, Narzt
, E.
, and Lackner
, F.
, 1997
, “Mild Intraoperative Hypothermia Prolongs Postanesthetic Recovery
,” Anesthesiology
, 87
(6
), pp. 1318
–1323
.10.1097/00000542-199712000-0000910.
Neading
, R.
, Scarborough
, T.
, O'Connell
, M.
, Leasiolagi
, J.
, Little
, M.
, Burgess
, J.
, Hargrove
, M.
, Goodfellow
, A.
, et al., 2023
, “Approach to Handling Atypical Field Blood Transfusion Scenarios
,” J. Spec. Oper. Med.
, 23
(1
), pp. 74
–79
.10.55460/KGHH-TT8111.
Singleton
, W.
, McLean
, M.
, Smale
, M.
, Alkhalifah
, M.
, Kosahk
, A.
, Ragina
, N.
, Cheng
, C. I.
, and Figg
, B. J.
, 2017
, “An Analysis of the Temperature Change in Warmed Intravenous Fluids During Administration in Cold Environments
,” Air Med. J.
, 36
(3
), pp. 127
–130
.10.1016/j.amj.2016.07.03212.
Indrani
, G.
, and Haldar
, R.
, 2019
, “Blood Warming in Trauma Related Transfusions-Precepts and Practices
,” J. Cardiovasc. Med. Cardiol.
, 6
(4
), pp. 094
–097
.10.17352/2455-2976.00010113.
Uhl
, L.
, Pacini
, D.
, and Kruskall
, M. S.
, 1992
, “A Comparative Study of Blood Warmer Performance
,” Anesthesiology
, 77
(5
), pp. 1022
–1028
.10.1097/00000542-199211000-0002614.
Smallman
, J. M.
, and Morgan
, M.
, 1992
, “Evaluation of The Level 1 Hotline Blood Warmer
,” Anaesthesia
, 47
(10
), pp. 869
–871
.10.1111/j.1365-2044.1992.tb03152.x15.
Presson
, R. G.
, Jr., Hillier
, S. C.
, and Haselby
, K. A.
, 1991
, “Blood or Fluid Warmers?
,” Anaesthesia
, 46
(4
), pp. 319
–319
.10.1111/j.1365-2044.1991.tb11514.x16.
Patel
, N.
, Knapke
, D. M.
, Smith
, C. E.
, Napora
, T. E.
, Pinchak
, A. C.
, and Hagen
, J. F.
, 1996
, “Simulated Clinical Evaluation of Conventional and Newer Fluid-Warming Devices
,” Anesth. Analgesia
, 82
(3
), pp. 517
–524
.10.1097/00000539-199603000-0001617.
Horowitz
, P. E.
, Delagarza
, M. A.
, Pulaski
, J. J.
, and Smith
, R. A.
, 2004
, “Flow Rates and Warming Efficacy With Hotline and Ranger Blood/Fluid Warmers
,” Anesth. Analg.
, 99
(3
), pp. 788
–792
.10.1213/01.ANE.0000129995.42008.A418.
Dubick
, M. A.
, Brooks
, D. E.
, Macaitis
, J. M.
, Bice
, T. G.
, Moreau
, A. R.
, and Holcomb
, J. B.
, 2005
, “Evaluation of Commercially Available Fluid-Warming Devices for Use in Forward Surgical and Combat Areas
,” Military Med.
, 170
(1
), pp. 76
–82
.10.7205/MILMED.170.1.7619.
Satoh
, J.
, Yamakage
, M.
, Wasaki
, S. I.
, and Namiki
, A.
, 2006
, “Performance of Three Systems For Warming Intravenous Fluids At Different Flow Rates
,” Anaesth. Intensive Care
, 34
(1
), pp. 46
–50
.10.1177/0310057X060340010920.
Bruells
, C. S.
, Bruells
, A. C.
, Rossaint
, R.
, Stoppe
, C.
, Schaelte
, G.
, and Zoremba
, N.
, 2013
, “A Laboratory Comparison of The Performance of The Buddy Lite™ and Enflow™ Fluid Warmers
,” Anaesthesia
, 68
(11
), pp. 1161
–1164
.10.1111/anae.1241521.
Zoremba
, N.
, Bruells
, C.
, Rossaint
, R.
, and Breuer
, T.
, 2018
, “Heating Capabilities of Small Fluid Warming Systems
,” BMC Anesthesiol
, 18
(1
), p. 98
.10.1186/s12871-018-0565-x22.
Lehavi
, A.
, Yitzhak
, A.
, Jarassy
, R.
, Heizler
, R.
, Katz
, Y. S.
, and Raz
, A.
, 2018
, “Comparison of The Performance of Battery-Operated Fluid Warmers
,” Emergency Med. J.
, 35
(9
), pp. 564
–570
.10.1136/emermed-2017-20711223.
Blakeman
, T.
, Fowler
, J.
, Branson
, R.
, Petro
, M.
, and Rodriquez
, D.
, 2021
, “Performance Characteristics of Fluid Warming Technology in Austere Environments
,” J. Spec. Oper. Med.
, 21
(1
), pp. 18
–24
.10.55460/0C2R-LNPH24.
Weatherall
, A.
, Gill
, M.
, Milligan
, J.
, Tetlow
, C.
, Harris
, C.
, Garner
, A.
, and Lee
, A.
, 2019
, “Comparison of Portable Blood-Warming Devices Under Simulated Pre-Hospital Conditions: A Randomised In-Vitro Blood Circuit Study
,” Anaesthesia
, 74
(8
), pp. 1026
–1032
.10.1111/anae.1468025.
Vallier
, D. J.
, Anderson
, W. J. L.
, Snelson
, J. V.
, Yauger
, Y. J.
, Felix
, J. R.
, Alford
, K. I.
, and Bermoy
, W. A.
, 2022
, “Comparison of Warming Capabilities Between Buddy Lite, enFlow, and Thermal Angel for U.S. Army Medical Personnel in Austere Conditions: A Literature Review
,” J. Spec. Oper. Med.
, 22
(4
), pp. 9
–13
.10.55460/HFTS-LQNF26.
Wilson
, K.
, Fourtounas
, M.
, and Anamourlis
, C.
, 2022
, “A Comparison of the Warming Capabilities of Two Baragwanath Rewarming Appliances With the Hotline Fluid Warming Device
,” South. Afr. J. Crit. Care.
, 38
(3
), pp. 96
–101
.10.7196/SAJCC.2022.v38i3.54927.
Thongsukh
, V.
, Kositratana
, C.
, and Jandonpai
, A.
, 2018
, “Effect of Fluid Flow Rate on Efficacy of Fluid Warmer: An In Vitro Experimental Study
,” Anesthesiol. Res. Pract.
, 2018
, pp. 1
–4
.10.1155/2018/879212528.
Browne
, D. A.
, de Boeck
, R.
, and Morgan
, M.
, 1990
, “An Evaluation of The Level 1 Blood Warmer Series
,” Anaesthesia
, 45
(11
), pp. 960
–963
.10.1111/j.1365-2044.1990.tb14631.x29.
Milligan
, J.
, Lee
, A.
, Gill
, M.
, Weatherall
, A.
, Tetlow
, C.
, and Garner
, A. A.
, 2016
, “Performance Comparison of Improvised Prehospital Blood Warming Techniques and a Commercial Blood Warmer
,” Injury
, 47
(8
), pp. 1824
–1827
.10.1016/j.injury.2016.05.03830.
DeClerck
, M. P.
, Lipman
, G. S.
, Grahn
, D. A.
, Cao
, V.
, Wieland
, M.
, Troxel
, T.
, and Heller
, H. C.
, 2015
, “A Chemical Heat Pack-Based Method for Consistent Heating of Intravenous Fluids
,” Wilderness Environ. Med.
, 26
(3
), pp. 412
–416
.10.1016/j.wem.2015.02.00431.
Platts-Mills
, T. F.
, Stendell
, E.
, Lewin
, M. R.
, Moya
, M. N.
, Dhah
, K.
, Stroh
, G.
, and Shalit
, M.
, 2007
, “An Experimental Study of Warming Intravenous Fluid in a Cold Environment
,” Wilderness Environ. Med.
, 18
(3
), pp. 177
–185
.10.1580/06-WEME-OR-051R1.132.
Roxby
, D.
, Sobieraj-Teague
, M.
, von Wielligh
, J.
, Sinha
, R.
, Kuss
, B.
, Smith
, A. L.
, and McEwen
, M.
, 2020
, “Warming Blood Prior to Transfusion Using Latent Heat
,” Emerg. Med. Australas.
, 32
(4
), pp. 604
–610
.10.1111/1742-6723.1347133.
Rodriguez
, A.
, Algaze
, I.
, Almog
, R.
, and Katzer
, R. J.
, 2021
, “Heating Intravenous Fluid Tubing in an Experimental Setting for Prehospital Hypothermia
,” Air Med. J.
, 40
(1
), pp. 41
–44
.10.1016/j.amj.2020.10.00934.
McEwen
, M. P.
, and Roxby
, D.
, 2007
, “Can Latent Heat Safely Warm Blood? – In Vitro Testing of A Portable Prototype Blood Warmer
,” BMC Emerg. Med.
, 7
(1
), Article No. 8.10.1186/1471-227X-7-835.
Piek
, R.
, and Stein
, C.
, 2013
, “Three Insulation Methods to Minimize Intravenous Fluid Administration Set Heat Loss
,” Prehospital Emerg. Care
, 17
(1
), pp. 68
–72
.10.3109/10903127.2012.70219036.
Lyng
, J. W.
, Perlmutter
, M. C.
, and West
, M. A.
, 2021
, “A Simple Improvised Prehospital Method to Warm Intravenous Fluid
,” J. Am. Coll. Emerg. Physicians Open.
, 2
(5
), p. e12536
.10.1002/emp2.12536
