Needle biopsy is a routine medical procedure for examining tissue or biofluids for the presence of disease using standard methods of pathology. The finite element analysis (FEA) methodology can provide guidance for optimizing the geometric parameters. The needle biopsy is simulated and analyzed while varying the needle angle, the aperture size and the slice-push ratio k. The results indicate that tissue reaction force in the axial direction of needle gradually decreases, and the stress and strain are more concentrated at the tip of needle with the increases of tip angle; the tissue reaction force decreases, and the torque increases while the slice-push ratio increases; and higher slice–push ratio can increase the peak stress concentration on the cutting edge and deformation of tissue; in the process of core needle cutting, increasing slice–push ratio can reduce the tissue reaction force significantly. While the aperture on distal wall of outer cannula becomes wider, the tissue reaction force increases significantly, and the cutting process will be more unstable. The results have the potential to provide important insight for improving the needle biopsy design process.

References

References
1.
Ough
,
M.
,
Velasco
,
J.
, and
Hieken
,
T. J.
,
2011
, “
A Comparative Analysis of Core Needle Biopsy and Final Excision for Breast Cancer: Histology and Marker Expression
,”
Am. J. Surg.
,
201
(
5
), pp.
685
687
.
2.
Liu
,
J.
,
Cooks
,
R. G.
, and
Ouyang
,
Z.
,
2011
, “
Biological Tissue Diagnostics Using Needle Biopsy and Spray Ionization Mass Spectrometry
,”
Anal. Chem.
,
83
(
24
), pp.
9221
9225
.
3.
Nguyen
,
B. M.
,
Halprin
,
C.
,
Olimpiadi
,
Y.
,
Traum
,
P.
,
Yeh
,
J. J.
, and
Dauphine
,
C.
,
2014
, “
Core Needle Biopsy is a Safe and Accurate Initial Diagnostic Procedure for Suspected Lymphoma
,”
Am. J. Surg.
,
208
(
6
), pp.
1003
1008
.
4.
Gong
,
Y.
,
Zheng
,
N.
,
Chen
,
S.
,
Xiao
,
Z.
,
Wu
,
M.
,
Liu
,
Y.
, and
Zeng
,
Q.
,
2014
, “
Ten Years' Experience With Needle Biopsy in the Early Diagnosis of Sacroiliitis
,”
Arthritis Rheum.
,
64
(
5
), pp.
1399
1406
.
5.
Okamura
,
A. M.
,
Simone
,
C.
, and
O'Leary
,
M. D.
,
2004
, “
Force Modeling for Needle Insertion Into Soft Tissue
,”
IEEE Trans. Biomed. Eng.
,
51
(
10
), pp.
1707
1716
.
6.
Abolhassani
,
N.
,
Patel
,
R.
, and
Moallem
,
M.
,
2007
, “
Needle Insertion Into Soft Tissue: A Survey
,”
Med. Eng. Phys.
,
29
(
4
), pp.
413
431
.
7.
Han
,
P.
,
Che
,
D.
,
Pallav
,
K.
, and
Ehmann
,
K.
,
2012
, “
Models of the Cutting Edge Geometry of Medical Needles With Applications to Needle Design
,”
Int. J. Mech. Sci.
,
65
(
1
), pp.
157
167
.
8.
Abolhassani
,
N.
,
Patel
,
R.
, and
Moallem
,
M.
,
2004
, “
Experimental Study of Robotic Needle Insertion in Soft Tissue
,”
Int. Congr.
,
1268
, pp.
797
802
.
9.
DS Simulia,
2009
, “
SIMULIA Abaqus Documentation—Abaqus User Subroutines Reference Manual
,” DS Simulia, Providence, RI.
10.
Zhang
,
Y.
, and
Tu
,
F.
,
2011
, “
The Physical Modeling of Flexible Needle Biopsy Soft Tissue Based on ABAQUS Software
,”
IEEE/ICME
International Conference on Complex Medical Engineering
, Harbin Heilongjiang, China, May 22–25, pp.
426
430
.
11.
Lin
,
C.
,
Coffey
,
D.
,
Erdman
,
A.
, and
Keefe
,
D.
,
2012
, “
A Framework for Medical Device Design Using CAD Synchronization and Remote High-Performance FEA Computing
,”
ASME J. Med. Devices
,
6
(
1
), p.
017577
.
12.
Alastrué
,
V.
,
Rodríguez
,
J. F.
,
Calvo
,
B.
, and
Doblaré
,
M.
,
2007
, “
Structural Damage Models for Fibrous Biological Soft Tissues
,”
Int. J. Solids Struct.
,
44
(
18–19
), pp.
5894
5911
.
13.
Dimaio
,
S. P.
, and
Salcudean
,
S. E.
,
2003
, “
Needle Insertion Modeling and Simulation
,”
IEEE Trans. Rob. Autom.
,
19
(
5
), pp.
864
875
.
14.
Mohsen
,
M.
, and
Dupont
,
P. E.
,
2010
, “
Mechanics of Dynamic Needle Insertion Into a Biological Material
,”
IEEE Trans. Bio-Med. Eng.
,
57
(
4
), pp.
934
943
.
15.
Han
,
P.
, and
Ehmann
,
K.
,
2013
, “
Study of the Effect of Cannula Rotation on Tissue Cutting for Needle Biopsy
,”
Med. Eng. Phys.
,
35
(
11
), pp.
1584
1590
.
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