Over the past 40 years, clinical use of endoclips has been extended from gastrointestinal (GI) hemostasis to the fixation of stents/catheters and for other interventions. Moreover, closure by endoclips are now broadly accepted by endoscopists and considered as the standard treatment of GI perforations for its convenience, avoiding surgical treatment, and reliable outcome [1–6].

Several single-firing devices are available in market: QuickClip2, QuickClip Pro, Resolution Clip, Instinct Clip, and Over-the-Scope Clip (OTSC) [7–9]. Although the multifiring device Clipmaster3 can deploy three clips at a time, the efficacy of this device is not proved as there is no clinical or experimental report [10].

In general, the size of perforation is less than 1.5 cm and it is too big to be closed with only five clips (expect for OTSC, which has a larger size and will...

References

References
1.
Hayashi
,
T.
,
Yonezawa
,
M.
, and
Kawabara
,
T.
,
1975
, “
The Study on Staunch Clip for the Treatment by Endoscopy
,”
Gastroenterol. Endosc.
,
17
, pp.
92
101
.
2.
Raju
,
G. S.
, and
Gajula
,
L.
,
2004
, “
Endoclips for GI Endoscopy
,”
Gastrointest. Endoscopy
,
59
(
2
), pp.
267
279
.
3.
Hepworth
,
C. C.
, and
Swain
,
C. P.
,
2000
, “
Mechanical Endoscopic Methods of Haemostasis for Bleeding Peptic Ulcers: A Review
,”
Baillieres Best Pract. Res. Clin. Gastroenterol.
,
14
(
3
), pp.
467
476
.
4.
Grupka
,
M. J.
, and
Benson
,
J.
,
2008
, “
Endoscopic Clipping
,”
J. Dig. Dis.
,
9
(
2
), pp.
72
78
.
5.
Sedarat
,
A.
,
2015
, “
Clips for Closure of Full Thickness Defects
,”
Tech. Gastrointest. Endoscopy
,
17
(
3
), pp.
129
135
.
6.
Raju
,
G. S.
,
2014
, “
Endoscopic Clip Closure of Gastrointestinal Perforations, Fistulae, and Leaks
,”
Dig. Endoscopy
,
26
(
S1
), pp.
95
104
.
7.
Chuttani
,
R.
,
Barkun
,
A.
,
Carpenter
,
S.
,
Chotiprasidhi
,
P.
,
Ginsberg
,
G. G.
,
Hussain
,
N.
,
Liu
,
J.
,
Silverman
,
W.
,
Taitelbaum
,
G.
, and
Petersen
,
B.
,
2006
, “
Endoscopic Clip Application Devices
,”
Gastrointest. Endoscopy
,
63
(
6
), pp.
746
750
.
8.
Yeh
,
R. W.
,
Kaltenbach
,
T.
, and
Soetikno
,
R.
,
2006
, “
Endoclips
,”
Tech. Gastrointest. Endoscopy
,
8
(
1
), pp.
2
11
.
9.
Kirschniak
,
A.
,
Subotova
,
N.
,
Zieker
,
D.
,
Königsrainer
,
A.
, and
Kratt
,
T.
,
2011
, “
The Over-the-Scope Clip (OTSC) for the Treatment of Gastrointestinal Bleeding, Perforations, and Fistulas
,”
Surg. Endoscopy
,
25
(
9
), pp.
2901
2905
.
10.
Bittinger
,
M.
, and
Messmann
,
H.
,
2008
, “
Endoscopic Therapy With a Novel Multiple Clip Applicator (Clipmaster3) in the Upper and Lower GI-Tract
,”
Gastrointest. Endoscopy
,
67
(
5
), p.
AB146
.
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