Industry 4.0 represents the Fourth Industrial Revolution and can be used as a framework to address all aspects of product realization including the challenges arising in the integration of cyber-systems and physical resources. The emerging paradigm of Industry 4.0 poses new systems design problems at the interface of smart manufacturing, robust and flexible automation, distributed and reconfigurable production systems, industrial IoT, and supply chain integration. Design engineering in the age of Industry 4.0 requires a new paradigm that deals with the sustainability of product and service, user experience and human satisfaction across a smart and connected value chain, as well as the distributed and networked aspect of the product realization processes. This Special Issue is dedicated to recent advances in design engineering in the age of Industry 4.0. Original papers with an explicit relevance to design issues such as design synthesis, modeling, and analysis or...

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