We demonstrate the bubble generation in a microfluidic channel by both experimental observation and numerical simulations. The microfluidic channel contains a nozzle-shaped actuation chamber with an acoustic resonator profile. The actuation is generated by a piezoelectric disk below the chamber. It was observed that for a steady deionized (DI) water flow driven through the channel, bubbles occurred in the channel when the piezoelectric disk was actuated at frequencies between 1 kHz and 5 kHz. Outside this actuation frequency range, no bubble generation was observed in the channel. The experiment showed that the presence of bubbles in this frequency range could significantly enhance the fluid mixing in the microfluidic channel, which otherwise would not happen at all without the bubbles. To further understand the bubble generation, the flow field in the microchannel was numerically simulated by a two-dimensional model. The numerical results show that there is a low pressure region inside the actuation chamber where water pressure is below the corresponding vapor pressure and thus bubbles can be generated. The bubble generation was also experimentally observed in the microchannel by using a high speed camera.

References

1.
Yang
,
Z.
,
Matsumoto
,
S.
,
Goto
,
H.
,
Matsumoto
,
M.
, and
Maeda
,
R.
, 2001, “
Ultrasonic Micromixer for Microfluidic Systems
,”
Sens, Actuators, A
,
93
(
3
), pp.
266
272
.
2.
Garstecki
,
P.
,
Fischbach
,
M. A.
, and
Whitesides
,
G. M.
, 2005, “
Design for Mixing Using Bubbles in Branched Microfluidic Channels
,”
Appl. Phys. Lett.
,
86
(
24
), pp.
1
3
.
3.
Garstecki
,
P.
,
Fuerstman
,
M. J.
,
Fischbach
,
M. A.
,
Sia
,
S. K.
, and
Whitesides
,
G. M.
, 2006, “
Mixing With Bubbles: A Practical Technology for Use With Portable Microfluidic Devices
,”
Lab Chip
,
6
(
2
), pp.
207
212
.
4.
Mao
,
X.
,
Juluri
,
B. K.
,
Lapsley
,
M. I.
,
Stratton
,
Z. S.
, and
Huang
,
T. J.
, 2010, “
Milliseconds Microfluidic Chaotic Bubble Mixer
,”
Microfluid. Nanofluid.
,
8
(
1
), pp.
139
144
.
5.
Liu
,
R. H.
,
Yang
,
J.
,
Pindera
,
M. Z.
,
Athavale
,
M.
, and
Grodzinski
,
P.
, 2002, “
Bubble-Induced Acoustic Micromixing
,”
Lab Chip
,
2
(
3
), pp.
151
157
.
6.
Ahmed
,
D.
,
Mao
,
X.
,
Shi
,
J.
,
Juluri
,
B. K.
, and
Huang
,
T. J.
, 2009, “
A Millisecond Micromixer via Single-Bubble-Based Acoustic Streaming
,”
Lab Chip
,
9
(
18
), pp.
2738
2741
.
7.
Ahmed
,
D.
,
Mao
,
X.
,
Juluri
,
B. K.
, and
Huang
,
T. J.
, 2009, “
A Fast Microfluidic Mixer Based on Acoustically Driven Sidewall-Trapped Microbubbles
,”
Microfluid. Nanofluid.
,
7
(
5
), pp.
727
731
.
8.
Wang
,
S. S.
,
Jiao
,
Z. J.
,
Huang
,
X. Y.
,
Yang
,
C.
, and
Nguyen
,
N. T.
, 2009, “
Acoustically Induced Bubbles in a Microfluidic Channel for Mixing Enhancement
,”
Microfluid. Nanofluid.
,
6
(
6
), pp.
847
852
.
9.
Brujan
,
E. A.
,
Nahen
,
K.
,
Schmidt
,
P.
, and
Vogel
,
A.
, 2001, “
Dynamics of Laser-Induced Cavitation Bubbles Near an Elastic Boundary
,”
J. Fluid Mech.
,
433
, pp.
251
281
.
10.
Chen
,
H.
,
Li
,
X.
,
Wan
,
M.
, and
Wang
,
S.
, 2009, “
High-Speed Observation of Cavitation Bubble Clouds Near A Tissue Boundary in High-Intensity Focused Ultrasound Fields
,”
Ultrasonics
,
49
(
3
), pp.
289
292
.
11.
Tomita
,
Y.
,
Robinson
,
P. B.
,
Tong
,
R. P.
, and
Blake
,
J. R.
, 2002, “
Growth and Collapse of Cavitation Bubbles Near a Curved Rigid Boundary
,”
J. Fluid Mech.
,
466
, pp.
259
283
.
12.
Luther
,
S.
,
Mettin
,
R.
,
Koch
,
P.
, and
Lauterborn
,
W.
, 2001, “
Observation of Acoustic Cavitation Bubbles at 2250 Frames Per Second
,”
Ultrason. Sonochem.
,
8
(
3
), pp.
159
162
.
13.
Lu
,
L.
, and
Wu
,
J.
, 2008, “
Flow Behavior of Liquid-Solid Coupled System of Piezoelectric Micropump
,”
Fron. Mech. Eng. China
,
3
(
1
), pp.
50
54
.
14.
Wang
,
S. S.
,
Huang
,
X. Y.
, and
Yang
,
C.
, 2010, “
Valveless Micropump With Acoustically Featured Pumping Chamber
,”
Microfluid. Nanofluid.
,
8
(
4
), pp.
549
555
.
You do not currently have access to this content.