A numerical investigation is conducted to shed light on the reasons leading to different flame configurations in gas turbine (GT) combustion chambers of aeronautical interest. Large eddy simulations (LES) with a flamelet-based combustion closure are employed for this purpose to simulate the DLR-AT big optical single sector (BOSS) rig fitted with a Rolls-Royce developmental lean burn injector. The reacting flow field downstream this injector is sensitive to the intricate turbulent–combustion interaction and exhibits two different configurations: (i) a penetrating central jet leading to an M-shape lifted flame; or (ii) a diverging jet leading to a V-shaped flame. The LES results are validated using available BOSS rig measurements, and comparisons show the numerical approach used is consistent and works well. The turbulent–combustion interaction model terms and parameters are then varied systematically to assess the flame behavior. The influences observed are discussed from physical and modeling perspectives to develop physical understanding on the flame behavior in practical combustors for both scientific and design purposes.