Abstract

A case of carbamate pesticide poisoning of a pregnant woman by carbofuran ingestion is presented. The mother recovered from the poisoning in the hospital but necrosis of the fetus was found. Toxicological findings of the liver, brain, and kidney of the fetus revealed carbofuran in concentrations comparable with the mother's blood. Our findings in the case contribute to the research on permeation of the placental barrier by chemical substances.

Issue Section:
Research Papers
Keywords:
pathology and biology, poisoning, carbamate pesticides, carbofuran, fetal necrosis, placental barrier

References

1.
Jaraczewska
,
W.
 and
Szymańska
,
S.
, “
New Pesticides Brought into the Trade Turnover in the Years 1977–78
,” presented at the
First Symposium of the Toxicological Section of the Polish Medicine in Practice Society
,
Lódź
,
1980
.
2.
Różanski
,
L.
, “
Metabolizm, degradacja i toksyczność pestycydów. II. Insektycydy karbaminianowe
,”
Wiadomości chemiczne
, Vol.
39
,
1985
, p. 225.
3.
Mayer
,
W. J.
 and
Greenberg
,
M. S.
, “
Determination of Some Carbamate Pesticides by High-Performance Liquid Chromatography with Electrochemical Detection
,”
Journal of Chromatography
 0021-9673, Vol.
208
,
1981
, pp.
295
-
304
.
Google Scholar
Crossref
Search ADS
 
4.
Zhong
,
W. Z.
,
Lemley
,
A. T.
, and
Spalik
,
J.
, “
Quantitative Determination of ppb Levels of Carbamate Pesticides in Water by Capillary Gas Chromatography
,”
Journal of Chromatography
 0021-9673, Vol.
299
,
1984
, pp.
269
-
274
.
Google Scholar
Crossref
Search ADS
PubMed
 
5.
Osselton
,
M. D.
 and
Snelling
,
R. D.
, “
Chromatographic Identification of Pesticides
,”
Journal of Chromatography
 0021-9673, Vol.
368
,
1986
, pp.
265
-
271
.
Google Scholar
Crossref
Search ADS
PubMed
 
6.
Follweiler
,
J. M.
 and
Sherma
,
J.
,
CRC Handbook of Chromatography: Pesticides and Related Organic Chemicals
, Vol.
1
,
CRC Press
,
Boca Raton, FL
,
1984
.
7.
Groszek
,
B.
,
Chrostek-Maj
,
J.
,
Zajac
,
J. J.
,
Kała
,
M.
, and
Dudek
,
J.
, “
Hemoperfusion as a Method of Treatment in Oral Poisoning with Carbamates
,” presented at the
Second Symposium of the Progress of Clinical Toxicology
,
Kraków
,
10
1986
.
This content is only available via PDF.
All rights reserved. This material may not be reproduced or copied, in whole or in part, in any printed, mechanical, electronic, film, or other distribution and storage media, without the written consent of ASTM International.
You do not currently have access to this content.