Abstract
Levels of carboxyhemoglobin that would ordinarily cause little or no noticeable symptoms or other effects proved fatal in individuals suffering from atherosclerotic coronary artery disease. All such deaths that occurred in the Cuyahoga County during a period of 23 years were studied. The pathophysiologic mechanisms that may be operative in these deaths are discussed. The importance of being aware of this fact, while one determines the cause and manner of such deaths, is stressed.
References
1.
Sunderman
, F. W.
and Sunderman
, F. W.
, Laboratory Diagnosis of Disease Caused by Toxic Agents
, Warren H. Green
, St. Louis, MO
, 1970
, pp. 259
-277
.2.
Spitz
, W. U.
and Fisher
, R. S.
, Medicolegal Investigation of Death
, Charles C Thomas
, Springfield, IL
, 1980
, pp. 305 and 341.3.
“
Operator's Manual IL182 CO-Oximeter
,” Instrumentation Laboratory
, Lexington, MA 02173
, 79182/05
1979
/Rev. 2.4.
Sodeman
, W. A.
and Sodeman
, W. A.
, Jr., Pathologic Physiology (Mechanisms of Disease)
, W. B. Saunders Co.
, Philadelphia
, 1967
, Chapter 19, pp. 381
-436
.5.
Ayres
, S.
, Archives of Environmental Health
0003-9896, Vol. 18
, 04
1969
, pp. 699
-709
.6.
Haldane
, J. B. S.
, Journal of Physiology
(London), Vol. 18
, 07
1895
, pp. 430
-462
.7.
8.
Haggard
, H. W.
, American Journal of Physiology
0002-9513, Vol. 56
, No. 3
, 07
1921
, pp. 390
-403
.9.
Chiodi
, H.
, Dill
, D. B.
, Consolazio
, and Horvath
, I. M.
, American Journal of Physiology
0002-9513, Vol. 134
, No. 4
, 11
1941
, pp. 683
-693
.10.
Chevalier
, R. B.
, Journal of American Medical Association
, Vol. 198
, No. 10
, 12
1966
, pp. 1061
-1064
.11.
Scharf
, S. M.
, Thames
, M. D.
, and Sargent
, R. K.
, The New England Journal of Medicine
, Vol. 291
, No. 2
, 11
07
1974
, pp. 85
-86
.12.
Warburg
, O.
, Heavy Metal Prosthetic Groups and Enzyme Action
, Clarendon Press
, Oxford
, 1949
.13.
Ball
, E. G.
, Journal of Biological Chemistry
0021-9258, Vol. 193
, No. 2
, 12
1951
, pp. 635
-647
.14.
Chance
, B.
, Annals of the New York Academy of Sciences
0077-8923, Vol. 174
, 10
1970
, pp. 193
-204
.15.
Goldbaum
, L. R.
, Aviation Space and Environmental Medicine
0095-6562, Vol. 46
, 10
1975
, pp. 1289
-1291
.16.
Goldbaum
, L. R.
, Aviation Space and Environmental Science
, Vol. 48
, No. 10
, 10
1977
, pp. 969
-970
.17.
Guy
, C. R.
, American Heart Journal
0002-8703, Vol. 82
, No. 6
, 12
1971
, pp. 824
-832
.18.
Wittenberg
, J. B.
, Journal of Biological Chemistry
0021-9258, Vol. 241
, No. 1
, 01
1966
, pp. 104
-114
.
This content is only available via PDF.
All rights reserved. This material may not be reproduced or copied, in whole or in part, in any printed, mechanical, electronic, film, or other distribution and storage media, without the written consent of ASTM International.
You do not currently have access to this content.