In this study we implemented the network simulation techniques using macromodels (lumped models) for capillary driven flows in microfluidic networks. The flow characteristics in a flow junction, such as meniscus stretching and bifurcation, were studied and their effects on filling time as well as pressure drop were explored for various network configurations. The results from the network simulator are validated numerically using computational fluid dynamics (CFD) simulations by employing the volume-of-fluids (VOF) method. The predictions by the network simulator for free-surface flows in different microfluidic networks were found to be in good agreement with the results obtained from the VOF simulations for filling time and meniscus position.

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