Cryogen spray cooling is an auxiliary procedure to dermatologic laser surgery, which consists of precooling the superficial skin layer (epidermis) during laser irradiation of subsurface targets to avoid nonspecific epidermal thermal damage. While previous studies have investigated the interaction of cryogen sprays with microscopically smooth human skin models, it is important to recognize that real human skin surface is far from smooth. With the objective to provide physical insight into the interaction between cryogen sprays and human skin, we study the effect of surface roughness on the impact dynamics of single cryogen droplets falling on skin models of various roughnesses (0.570μm). We first develop a theoretical model to predict the maximum spread diameter (Dm) following droplet impingement based on a similarity approximation to the solution of a viscous boundary layer that incorporates friction as the major source of viscous dissipation on a rough surface. Then, we measure the droplet diameter, impact velocity, and Dm of cryogen droplets falling by gravity onto skin models. Experimental data prove that the proposed model predicts Dm with good accuracy, suggesting that the effects of surface roughness and friction on Dm are properly taken into account for the range of surface roughness studied herein.

1.
Kelly
,
K. M.
,
Nelson
,
J. S.
,
Lask
,
G. P.
,
Geronemus
,
R. G.
, and
Bernstein
,
L. J.
, 1999, “
Cryogen Spray Cooling in Combination With Nonablative Laser Treatment of Facial Rhytides
,”
Arch. Dermatol.
0003-987X,
135
(
6
), pp.
691
694
.
2.
Nelson
,
J. S.
,
Milner
,
T. E.
,
Anvari
,
B.
,
Tanenbaum
,
B. S.
,
Kimel
,
S.
,
Svaasand
,
L. O.
, and
Jacques
,
S. L.
, 1995, “
Dynamic Epidermal Cooling During Pulse-Laser Treatment of Port-Wine Stain: A New Methodology With Preliminary Clinical Evaluation
,”
Arch. Dermatol.
0003-987X,
131
(
6
), pp.
695
700
.
3.
Goldman
,
M. P.
, and
Fitzpatrick
,
R. E.
, 1999,
Cutaneous Laser Surgery
,
Mosby
,
Chicago
.
4.
Nelson
,
J. S.
,
Milner
,
T. E.
,
Anvari
,
B.
,
Tanenbaum
,
B. S.
,
Kimel
,
S.
,
Svaasand
,
L. O.
, and
Jacques
,
S. L.
, 1991, “
Selective Photothermolysis and Removal of Cutaneous Vasculopthies and Tattoos by Pulsed Laser
,”
Plast. Reconstr. Surg.
0032-1052,
88
(
4
), pp.
723
731
.
5.
Anvari
,
B.
,
Milner
,
T. E.
,
Tanenbaum
,
B. S.
,
Kimel
,
S.
,
Svaasand
,
L. O.
, and
Nelson
,
J. S.
, 1995, “
Dynamic Epidermal Cooling in Conjunction With Laser Treatment of Port-Wine Stains: Theoretical and Preliminary Clinical Evaluations
,”
Lasers Med. Sci.
0268-8921,
10
(
2
), pp.
105
112
.
6.
Aguilar
,
G.
,
Majaron
,
B.
,
Pope
,
K.
,
Svaasand
,
L. O.
,
Lavernia
,
E. J.
, and
Nelson
,
J. S.
, 2001, “
Influence of Nozzle-to-Skin Distance in Cryogen Spray Cooling for Dermatologic Laser Surgery
,”
Lasers Surg. Med.
0196-8092,
28
(
2
), pp.
113
120
.
7.
Aguilar
,
G.
,
Vu
,
H.
, and
Nelson
,
J. S.
, 2004, “
Influence of Angle Between the Nozzle and Skin Surface on the Heat Flux and Overall Heat Extraction During Cryogen Spray Cooling
,”
Phys. Med. Biol.
0031-9155,
49
(
10
), pp.
N147
N153
.
8.
Aguilar
,
G.
,
Majaron
,
B.
,
Verkruysse
,
W.
,
Zhou
,
Y.
,
Nelson
,
J. S.
, and
Lavernia
,
E. J.
, 2001, “
Theoretical and Experimental Analysis of Droplet Diameter, Temperature, and Evaporation Rate Evolution in Cryogenic Sprays
,”
Int. J. Heat Mass Transfer
0017-9310,
44
, pp.
3201
3211
.
9.
Aguilar
,
G.
,
Majaron
,
B.
,
Karapetian
,
E.
,
Lavernia
,
E. J.
, and
Nelson
,
J. S.
, 2003, “
Experimental Study of Cryogen Spray Properties for Application in Dermatologic Laser Surgery
,”
IEEE Trans. Biomed. Eng.
0018-9294,
50
(
7
), pp.
863
869
.
10.
Franco
,
W.
,
Vu
,
H.
,
Jia
,
W.
,
Nelson
,
J. S.
, and
Aguilar
,
G.
, 2007, “
Fluid and Thermal Dynamics of Cryogen Sprays Impinging on a Human Tissue Phantom
,”
ASME J. Biomech. Eng.
0148-0731, accepted for publication.
11.
Aguilar
,
G.
,
Wang
,
G. X.
, and
Nelson
,
J. S.
, 2003, “
Dynamic Behavior of Cryogen Spray Cooling: Effects of Spurt Duration and Spray Distance
,”
Lasers Surg. Med.
0196-8092,
32
(
2
), pp.
152
159
.
12.
Gasljevic
,
K.
,
Aguilar
,
G.
, and
Matthys
,
E. F.
, 2001, “
On Two Distinct Types of Drag-Reducing Fluids, Diameter Scaling, and Turbulent Profiles
,”
J. Non-Newtonian Fluid Mech.
0377-0257,
96
(
3
), pp.
405
425
.
13.
Tunnell
,
J. W.
,
Torres
,
J. H.
, and
Anvari
,
B.
, 2002, “
Methodology for Estimation of Time-Dependent Surface Heat Flux Due to Cryogen Spray Cooling
,”
Ann. Biomed. Eng.
0090-6964,
30
(
1
), pp.
19
33
.
14.
Manuskiatti
,
W.
,
Schwindt
,
D. A.
, and
Maibach
,
H. I.
, 1998, “
Influence of Age, Anatomic Site and Race on Skin Roughness and Scaliness
,”
Dermatology (Basel, Switz.)
1018-8665,
196
(
4
), pp.
401
407
.
15.
Chandra
,
S.
, and
Avedisian
,
C. T.
, 1991, “
On the Collision of a Droplet With a Solid-Surface
,”
Proc. R. Soc. London, Ser. A
1364-5021,
432
(
1884
), pp.
13
41
.
16.
Frohn
,
A.
, and
Roth
,
N.
, 2000,
Dynamics of Droplets
,
Springer
,
New York
.
17.
Pasandideh-Fard
,
M.
,
Qiao
,
Y. M.
,
Chandra
,
S.
, and
Mostaghimi
,
J.
, 1996, “
Capillary Effects During Droplet Impact on a Solid Surface
,”
Phys. Fluids
1070-6631,
8
(
3
), pp.
650
659
.
18.
White
,
F. M.
, 1991,
Viscous Fluid Flow
,
McGraw Hill
,
New York
.
19.
Mao
,
T.
, and
Kuhn
,
D.
, 1997, “
Spread and Rebound of Liquid Droplets Upon Impact on Flat Surfaces
,”
AIChE J.
0001-1541,
43
(
9
), pp.
2169
2179
.
20.
Lavernia
,
E. J.
, and
Wu
,
Y.
, 1996,
Spray Atomization and Deposition
,
Wiley
,
New York
.
21.
Rein
,
M.
, 1993, “
Phenomena of Liquid Drop Impact on Solid and Liquid Surface
,”
Fluid Dyn. Res.
0169-5983,
12
(
2
), pp.
61
93
.
22.
Prunet-Foch
,
B.
,
Legay
,
F.
,
Vignes-Adler
,
M.
, and
Delmotte
,
C.
, 1998, “
Impacting Emulsion Drop on a Steel Plate: Influence of the Solid Substrate
,”
J. Colloid Interface Sci.
0021-9797,
199
(
2
), pp.
151
168
.
23.
Rioboo
,
R.
,
Marengo
,
M.
, and
Tropea
,
C.
, 2002, “
Time Evolution of Liquid Drop Impact Onto Solid, Dry Surfaces
,”
Exp. Fluids
0723-4864,
33
(
1
), pp.
112
124
.
24.
Moita
,
A.
, and
Moreira
,
A.
, 2003, “
Influence of Surface Properties on Dyanmic Behavior of Impacting Droplet
,”
Ninth International Conference on Liquid Atomization and Spray System
,
Sorrento
,
Italy
.
You do not currently have access to this content.