Transient Cavitation in Pre-Filled Syringes During Autoinjector Actuation

Cavitation has been observed in the cone of a syringe actuated by an autoinjector device. Numerical simulations were used to determine if the cone can enhance the collapse of a bubble. We found the collapse of a bubble in a cone can be more violent than the collapse of a bubble close to a flat wall or in a free space due to the reflected wave focusing on the axis of symmetry.