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BioNano Monographs

Nanoparticles and Brain Tumor Treatment

Editor
G. Caruso
G. Caruso
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M. Caffo
M. Caffo
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G. Raudino
G. Raudino
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F. Tomasello
F. Tomasello
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ISBN:
9780791860038
No. of Pages:
110
Publisher:
ASME Press
Publication date:
2012

Gliomas are the most common primary brain tumors in adults, with a worldwide incidence of approximately 7 out of 100,000 individuals per year. Although brain tumors constitute only a small proportion of overall human malignancies, they carry high rates of morbidity and mortality. Mortality is still close to 100% and the average survival of patients with glioblastoma multiforme (GBM) is less than 1 year when classical treatment is used. Recent progress in multimodal treatment of this disease has led to only a slight increase in average survival up to 15–18 months. The effectiveness of the actual chemotherapeutic approach and multimodal targeted therapies remains modest in gliomas.

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