Skip to Main Content
Skip Nav Destination
BioNano Monographs

Nanoparticles and Brain Tumor Treatment

Editor
G. Caruso
G. Caruso
Search for other works by this author on:
M. Caffo
M. Caffo
Search for other works by this author on:
G. Raudino
G. Raudino
Search for other works by this author on:
F. Tomasello
F. Tomasello
Search for other works by this author on:
ISBN:
9780791860038
No. of Pages:
110
Publisher:
ASME Press
Publication date:
2012

Genomic DNA aberrations are key genetic events in gliomagenesis. Recurrent genomic regions of alteration, including net gains and losses, have been found in gliomas. Whereas some of these regions contain known oncogenes and tumor suppressor genes, the biologically relevant genes within other regions remain to be identified. The phenotypic and genotypic heterogeneity indicate that no isolated genetic event accounts for gliomagenesis, but rather the cumulative effects of a number of alterations that operate in a concerted manner. In this pathological process are included various biological events, such as activation of growth factor receptor signaling pathways, down-regulation of many apoptotic mechanisms,...

2.1 Invasion and angiogenesis
This content is only available via PDF.
You do not currently have access to this chapter.
Close Modal

or Create an Account

Close Modal
Close Modal