This paper explains the hardware implementation of the Quadrature Phase Shift Keying (QPSK) Transmitter for Biomedical Applications as a new approach in transmitting the electrocardiography (ECG) signals. The paper analyses the QPSK theoretical principle along with Electrocardiography (ECG) transmission approaches. The proposed methodology can remove the AWGN present in the biomedical input signal and thereby offer better QPSK transmitter output signal.