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Biomedical Applications of Vibration and Acoustics in Imaging and Characterizations

Editor
Mostafa Fatim
Mostafa Fatim
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Ahmed Al-Jumaily
Ahmed Al-Jumaily
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ISBN-10:
0791802731
ISBN:
9780791802731
No. of Pages:
320
Publisher:
ASME Press
Publication date:
2008

Magnetic resonance elastography (MRE) is a non-invasive phase-contrast MR technique that directly visualizes and quantitatively measure propagating strain waves in tissue-like materials subject to harmonic mechanical excitation. A phase-contrast MRI technique is used to spatially map the shear wave displacement field, and local quantitative values of shear modulus are then calculated through various inversion algorithms, and elastogram generated. This information can be clinically useful to understand the effects of pathologies on the mechanical properties of skeletal muscle and to quantify the effects of treatment. In this chapter, the principles of MRE image acquisition and stiffness inversion algorithm are reviewed, specific instrumention to apply MRE on skeletal muscles are introduced, and unique challenges to MRE when applied on skeletal muscles are discussed.

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