International Conference on Software Technology and Engineering (ICSTE 2012)
16 Two-Dimension Simulation of a Red Blood Cell Partitioning in Microvascular Bifurcation
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A two-dimensional model based on the elastic and Euler-Bernoulli beam theory is proposed to simulate the behaviors of a red blood cell (RBC) crossing a microvascular bifurcation. The fluid dynamics is obtained by solving the discrete lattice Boltzmann equation. Simulations have exhibited the RBC configuration evolution in the asymmetrical flow assignation between the two downstream branches. The simulation results are found quite consistent to the experimental observations and computational results reported in other researches. Quantitative analysis reveals that for asymmetrical flow case, RBC has a stronger tendency to enter the branch with higher flow rate, which can block the local channel flow if it is compressed, and the blockage will rise if the RBC deformability gets lower.