The objective of this investigation was to provide a detailed evaluation of the heat affected zone properties of a high-strength pipeline steel. The X80 high-strength low-alloy microalloyed steel was supplied as a hot rolled plate with accelerated cooling. The four-wire tandem submerged arc welding process with different heat input was used to generate welded joints. The microstructure of the heat affected zone depended on heat input values. M/A constituent appeared in the microstructure of HAZ region for all of the specimens along the prior-austenite grain boundaries and between bainitic ferrite laths. Charpy impact specimens were notched in four locations: FL (fusion line), FL+1mm, FL+2mm and FL+3mm. The Charpy absorbed energy of specimens was assessed using Charpy impact testing at −50°C