Silica Nanoparticles as Drug Delivery System for Immunomodulator GMDP (Biomedical & Nanomedical Technologies - Concise Monograph Series)
1 Drug Delivery Nanosystems as a Promising Area of Modern Chemistry and Medicine. Silica Nanoparticles as Potential Drug Carriers
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In present time, besides searching for new pharmacologically active compounds, optimization of therapeutic indexes of well known drugs is a major challenge for many pharmaceutical companies. Often use of traditional drug formulations suffer from grave shortcomings such as poor solubility and bioavailability, rapid elimination from the blood, low specificity, necessity of overdoses and increased side effects, etc.
New technologies are applied for constructing innovative drug formulation. The strategy, often called drug delivery systems, allows improvement in the therapeutic index of both established and new drugs, and is based on an interdisciplinary approach that combines chemistry, pharmaceutics and medicine.