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Keywords: proteins
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Journal Articles
Journal Articles
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. October 2011, 133(10): 104504.
Published Online: November 7, 2011
... an applied stress cannot be due to the dynamics of the chondroitin sulfate chains because their relaxation times will be much too short. The chondroitin sulfate chains are attached to the proteoglycan core proteins, most of which are attached to hyaluronic acid polymers. As we argued above, despite the fact...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. September 2011, 133(9): 091011.
Published Online: October 14, 2011
.... Since the collagen fiber-alignment of these samples can be confirmed by polarized light microscopy, these cell-compacted tissue analogs will serve as convenient tests cases for GAIM. biological tissues biomechanics elastomers proteins anisotropy heterogeneous inverse mechanics soft...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. September 2011, 133(9): 091005.
Published Online: October 11, 2011
...-dimensional studies have shown that dynamic flow conditions (e.g., pulsatile oscillatory waveforms) elicit an enhanced mechanotransductive response and elevated expression of osteoblastic proteins relative to steady flow. However, dynamic perfusion of three-dimensional scaffolds has been primarily examined...
Journal Articles
Publisher: ASME
Article Type: Design Innovations
J Biomech Eng. September 2011, 133(9): 095001.
Published Online: October 11, 2011
... neurophysiology proteins stress-strain relations microstructure extracellular matrix two-photon sclera glaucoma multiphoton According to the World Health Organization, glaucoma is estimated to affect 80 × 10 6 people by 2020 worldwide, making it the second leading cause of blindness [( 1...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. September 2011, 133(9): 091002.
Published Online: October 4, 2011
... and eosin (H&E) along with antibodies for collagen types II (bone ends only) and III (mid-substance only). Patella and tibial bone ends were stained with antibodies for collagen type II because it is the primary structural protein of fibrocartilage found at the tendon-to-bone insertion site. Mid...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. July 2011, 133(7): 071007.
Published Online: July 18, 2011
... to model and predict the behavior under any load. Most ex vivo tests are performed within 24 h of dissection, so the tissue is still “alive.” For large elastic arteries; however, the passive mechanical behavior is attributed mostly to the very stable proteins, elastin, and collagen. If the testing...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. July 2011, 133(7): 071002.
Published Online: July 13, 2011
... cells can organize the collagen network maintaining an uniaxial distribution. 02 05 2010 17 03 2011 13 07 2011 13 07 2011 13 07 2011 biomechanics blood vessels molecular biophysics physiological models proteins tissue engineering The goal of small diameter...
Journal Articles
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. June 2011, 133(6): 064506.
Published Online: July 6, 2011
... cyclic loading biological tissues biomechanics elasticity molecular biophysics polarimetry proteins tensile strength 28 02 2011 09 05 2011 11 05 2011 06 07 2011 06 07 2011 2011 American Society of Mechanical Engineers ...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. May 2011, 133(5): 051002.
Published Online: April 8, 2011
... properties of the two main, passive, load-bearing components of the artery wall, elastin, and collagen. Elastin matrix proteins are modeled with an orthotropic neo-Hookean material. High stretch behavior is governed by an orthotropic crimped fiber material modeled as a planar sinusoidal linear elastic beam...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. January 2011, 133(1): 011010.
Published Online: December 23, 2010
... cellular biophysics deformation dissolving molecular biophysics physiological models proteins In the mathematical framework of continuum growth theories, two fundamental modes of growth are recognized: volumetric or interstitial growth and surface or appositional growth. In volumetric growth...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. November 2010, 132(11): 111008.
Published Online: October 20, 2010
... in the strengthening process. The predicted fiber dispersion (after 42 days) also appears to agree fairly well with the results presented by Huang et al. Collagen is a very important protein of the human body, and the ability of collagen fiber networks to remodel itself enables it to adjust to varying...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. July 2010, 132(7): 071002.
Published Online: May 14, 2010
... for the gap distance to decrease to asperity size. For realistic physiological parameters, the time for the surfaces to contact is a minimum of several minutes and likely much longer. The role of albumin in the synovial fluid is included because the large protein molecules are trapped by the small openings...
Journal Articles
Journal Articles
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. February 2010, 132(2): 024504.
Published Online: January 29, 2010
... internal stresses molecular biophysics physiological models proteins swelling triphasic theory cartilage curling inhomogeneity fixed charge density Osmotic pressure is critical for the development of biological tissues and the maintenance of normal functions. In the early development...
Journal Articles
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. February 2010, 132(2): 024502.
Published Online: January 28, 2010
... 10 2009 04 01 2010 28 01 2010 28 01 2010 biomechanics bone creep elastic moduli hardness mechanical stability molecular biophysics nanoindentation proteins viscoelasticity nanoindentation creep viscoelasticity viscosity bone matrix Bone...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. February 2010, 132(2): 021003.
Published Online: January 5, 2010
... to determine anisotropy effects in pregnant tissue. 28 11 2007 29 05 2009 05 01 2010 05 01 2010 biological organs biological tissues biomechanics biomedical MRI biorheology diagnostic radiography obstetrics proteins soft tissue mechanics cervical tissue cervical...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. February 2010, 132(2): 021001.
Published Online: December 28, 2009
... the expression of alkaline phosphatase (ALP) at the protein- and mRNA levels, as well as for calcium accumulation. The timing of HP stimulation affected hMSC proliferation and expression of ALP activity. HP stimulation after 6 days was most effective at promoting ALP activity. CS-containing matrices promoted...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. January 2010, 132(1): 011010.
Published Online: December 18, 2009
... apparent elastic modulus at an indentation strain of 30% from AFM measurements for each region and age correlated well with the long-term elastic modulus measured from 30% unconfined compression tests (slope not significantly different from 1, p > 0.05 ). Protein, lipid, and sulfated glycosaminoglycan...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. November 2009, 131(11): 111007.
Published Online: October 21, 2009
... on mechanical function of the bulk material with degeneration. 05 08 2008 19 02 2009 21 10 2009 biological tissues biomechanics molecular biophysics proteins tensile testing intervertebral disk degeneration tensile properties nonlinearity anisotropic hyperelastic model...