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Journal Articles

Enhancing Inhalation Drug Delivery: A Comparative Study and Design Optimization of a Novel Valved Holding Chamber

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Shahab Azimi, Siamak Arzanpour
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2024, 146(4): 041002.
Paper No: BIO-23-1276
https://doi.org/10.1115/1.4064436
Published Online: February 7, 2024
View Articletitled, Enhancing Inhalation Drug Delivery: A Comparative Study and Design Optimization of a Novel Valved Holding Chamber
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Topics: Design, Optimization, Particulate matter, Simulation, Valves, Drugs, Engineering prototypes, Flow (Dynamics), Drug delivery systems
Journal Articles

Fluid Flow Analysis of Neonatal Dual-Lumen Cannulas for Venovenous Extracorporeal Membrane Oxygenation

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Danielle M. Sawka, Yunxing Su, Julie Monteagudo, Roberto Zenit
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2024, 146(2): 021008.
Paper No: BIO-23-1237
https://doi.org/10.1115/1.4064212
Published Online: December 20, 2023
View Articletitled, Fluid Flow Analysis of Neonatal Dual-Lumen Cannulas for Venovenous Extracorporeal Membrane Oxygenation
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Topics: Circuits, Flow (Dynamics), Fluid dynamics, Geometry, Membranes, Shear stress, Particulate matter, Blood, Variable structure systems, Transparency
Journal Articles

Evaluation of Soft Mist Inhaler Aerosol Velocity, Size, and Deposition Inside the Mouth—A Computational Fluid Dynamics Study

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Taha Sadeghi, Leila Pakzad, Pedram Fatehi
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2023, 145(6): 061007.
Paper No: BIO-22-1147
https://doi.org/10.1115/1.4056967
Published Online: March 8, 2023
View Articletitled, Evaluation of Soft Mist Inhaler Aerosol Velocity, Size, and Deposition Inside the Mouth—A Computational Fluid Dynamics Study
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Topics: Aerosols, Computational fluid dynamics, Flow (Dynamics), Geometry, Nozzles, Particulate matter, Drugs
Journal Articles

Modeling the Mechanical Microenvironment of Coiled Cerebral Aneurysms

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David I. Bass, Laurel M. M. Marsh, Patrick Fillingham, Do Lim, V. Keshav Chivukula, Louis J. Kim, Alberto Aliseda, Michael R. Levitt
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2023, 145(4): 041005.
Paper No: BIO-22-1112
https://doi.org/10.1115/1.4055857
Published Online: December 5, 2022
View Articletitled, Modeling the Mechanical Microenvironment of Coiled Cerebral Aneurysms
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Topics: Aneurysms, Particulate matter, Domes (Structural elements), Simulation, Modeling, Flow (Dynamics), Thrombosis, Porosity, Shear stress
Includes: Supplementary data
Journal Articles

Influence of the Anatomical Structure on the Hemodynamics of Iliac Vein Stenosis

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Li Changsheng, Feng Haiquan, Wang Kun, Wang Xiaotian, Wang Yonggang
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2023, 145(1): 011013.
Paper No: BIO-21-1445
https://doi.org/10.1115/1.4055307
Published Online: September 19, 2022
View Articletitled, Influence of the Anatomical Structure on the Hemodynamics of Iliac Vein Stenosis
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Topics: Blood flow, Hemodynamics, Particulate matter, Shear stress, Vessels, Shear (Mechanics), Blood vessels, Flow (Dynamics), Computational fluid dynamics, Thrombosis
Journal Articles

Guiding the Prostatic Artery Embolization Procedure With Computational Fluid Dynamics

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Mostafa Mahmoudi, Chadrick Jennings, Keith Pereira, Andrew F. Hall, Amirhossein Arzani
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2022, 144(11): 111004.
Paper No: BIO-21-1381
https://doi.org/10.1115/1.4054515
Published Online: June 16, 2022
View Articletitled, Guiding the Prostatic Artery Embolization Procedure With Computational Fluid Dynamics
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Topics: Aorta, Blood flow, Computational fluid dynamics, Hemodynamics, Particulate matter, Bifurcation, Flow (Dynamics)
Journal Articles

A Novel Device for the Quantification of Synovial Fluid Viscosity Via Magnetic Deflection

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Samuel L. Armington, Yash Y. Shah, Jon Dobson, Kyle D. Allen
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. August 2022, 144(8): 084504.
Paper No: BIO-21-1357
https://doi.org/10.1115/1.4053794
Published Online: March 9, 2022
View Articletitled, A Novel Device for the Quantification of Synovial Fluid Viscosity Via Magnetic Deflection
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Topics: Deflection, Flow (Dynamics), Fluids, Viscosity, Particulate matter, Experimental design
Journal Articles

Ramifications of Vorticity on Aggregation and Activation of Platelets in Bi-Leaflet Mechanical Heart Valve: Fluid–Structure-Interaction Study

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Meraj Ahmed, Nirmal Gupta, Rashmoni Jana, Malay K. Das, Kamal K. Kar
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2022, 144(8): 081002.
Paper No: BIO-21-1102
https://doi.org/10.1115/1.4053665
Published Online: February 21, 2022
View Articletitled, Ramifications of Vorticity on Aggregation and Activation of Platelets in Bi-Leaflet Mechanical Heart Valve: Fluid–Structure-Interaction Study
Open the PDF for Ramifications of Vorticity on Aggregation and Activation of Platelets in Bi-Leaflet Mechanical Heart Valve: Fluid–Structure-Interaction Study in another window
Topics: Flow (Dynamics), Fluids, Particulate matter, Platelets, Vorticity, Heart valve prostheses
Journal Articles

Development of Three-Stage Bioaerosol Sampler for Size-Selective Sampling

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Jun-Hyung Lim, Sang Hwan Nam, Jongwoo Kim, Nam Hoon Kim, Gun-Soo Park, Jin-Soo Maeng, Se-Jin Yook
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2022, 144(7): 071008.
Paper No: BIO-21-1249
https://doi.org/10.1115/1.4053504
Published Online: February 18, 2022
View Articletitled, Development of Three-Stage Bioaerosol Sampler for Size-Selective Sampling
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Topics: Aerosols, Flow (Dynamics), Particulate matter, Fluids
Journal Articles

Stability of the Interface Between Two Immiscible Liquids in a Model Eye Subject to Saccadic Motion

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Ru Wang, Jheng-Han Tsai, Martin P. Snead, Philip Alexander, D. Ian Wilson
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. May 2022, 144(5): 051004.
Paper No: BIO-20-1459
https://doi.org/10.1115/1.4053004
Published Online: December 20, 2021
View Articletitled, Stability of the Interface Between Two Immiscible Liquids in a Model Eye Subject to Saccadic Motion
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Topics: Computational fluid dynamics, Flow (Dynamics), Fluids, Silicones, Simulation, Stability, Surface tension, Surfactants, Viscosity, Shapes
Includes: Supplementary data
Journal Articles

Review of the Development of Hemodynamic Modeling Techniques to Capture Flow Behavior in Arteries Affected by Aneurysm, Atherosclerosis, and Stenting

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Petra N. Williamson, Paul D. Docherty, Sina G. Yazdi, Adib Khanafer, Natalia Kabaliuk, Mark Jermy, Patrick H. Geoghegan
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2022, 144(4): 040802.
Paper No: BIO-20-1203
https://doi.org/10.1115/1.4053082
Published Online: December 17, 2021
View Articletitled, Review of the Development of Hemodynamic Modeling Techniques to Capture Flow Behavior in Arteries Affected by Aneurysm, Atherosclerosis, and Stenting
Open the PDF for Review of the Development of Hemodynamic Modeling Techniques to Capture Flow Behavior in Arteries Affected by Aneurysm, Atherosclerosis, and Stenting in another window
Topics: Computational fluid dynamics, Flow (Dynamics), Hemodynamics, Modeling, Particulate matter, Stents, Aneurysms, Boundary-value problems, Atherosclerosis, Fluids
Journal Articles

A First Assessment of an Aerodynamic Barrier Layer for Filtering Airborne Hygroscopic Particles

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Francisco J. Arias, Salvador De Las Heras
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2022, 144(2): 021006.
Paper No: BIO-21-1121
https://doi.org/10.1115/1.4052291
Published Online: September 23, 2021
View Articletitled, A First Assessment of an Aerodynamic Barrier Layer for Filtering Airborne Hygroscopic Particles
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Topics: Drops, Filtration, Particulate matter, Fibers
Journal Articles

Improving Pulmonary Nanotherapeutics Using Helical Aerosol Streams: An In Silico Study

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Adithya Gurumurthy, Clement Kleinstreuer
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2021, 143(11): 111001.
Paper No: BIO-21-1035
https://doi.org/10.1115/1.4051217
Published Online: July 14, 2021
View Articletitled, Improving Pulmonary Nanotherapeutics Using Helical Aerosol Streams: An In Silico Study
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Topics: Aerosols, Drugs, Flow (Dynamics), Nanoparticles, Particulate matter, Lung, Diffusion (Physics), Fluids, Drug delivery systems
Journal Articles

Computational Fluid Dynamics Study of Cerebral Thromboembolism Risk in Ventricular Assist Device Patients: Effects of Pulsatility and Thrombus Origin

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Ray Prather, Eduardo Divo, Alain Kassab, William DeCampli
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2021, 143(9): 091001.
Paper No: BIO-20-1332
https://doi.org/10.1115/1.4050819
Published Online: May 6, 2021
View Articletitled, Computational Fluid Dynamics Study of Cerebral Thromboembolism Risk in Ventricular Assist Device Patients: Effects of Pulsatility and Thrombus Origin
Open the PDF for Computational Fluid Dynamics Study of Cerebral Thromboembolism Risk in Ventricular Assist Device Patients: Effects of Pulsatility and Thrombus Origin in another window
Topics: Computational fluid dynamics, Flow (Dynamics), Particulate matter, Thrombosis, Risk, Unsteady flow, Ventricular assist devices
Includes: Supplementary data
Journal Articles

Impact-Induced Cortical Strain Concentrations at the Sulcal Base and Its Implications for Mild Traumatic Brain Injury

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Ashley Mazurkiewicz, Sheng Xu, Hanspeter Frei, Rohan Banton, Thuvan Piehler, Oren E. Petel
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2021, 143(6): 061015.
Paper No: BIO-20-1330
https://doi.org/10.1115/1.4050283
Published Online: March 24, 2021
View Articletitled, Impact-Induced Cortical Strain Concentrations at the Sulcal Base and Its Implications for Mild Traumatic Brain Injury
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Topics: Biological tissues, Brain, Particulate matter, Traumatic brain injury, Wounds, Shear (Mechanics)
Journal Articles

Visualizing the Flow Patterns in an Expanding and Contracting Pulmonary Alveolated Duct Based on Microcomputed Tomography Images

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Toshihiro Sera, Naoki Kamiya, Taichi Fukushima, Gaku Tanaka
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. July 2021, 143(7): 074501.
Paper No: BIO-20-1457
https://doi.org/10.1115/1.4050285
Published Online: March 24, 2021
View Articletitled, Visualizing the Flow Patterns in an Expanding and Contracting Pulmonary Alveolated Duct Based on Microcomputed Tomography Images
Open the PDF for Visualizing the Flow Patterns in an Expanding and Contracting Pulmonary Alveolated Duct Based on Microcomputed Tomography Images in another window
Topics: Ducts, Flow (Dynamics), Particulate matter, Deformation, Radial flow
Journal Articles

Time-Resolved Echo-Particle Image/Tracking Velocimetry Measurement of Interactions Between Native Cardiac Output and Veno-Arterial ECMO Flows

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Zeng Zhang, Xun Zhou, Alejandro Suarez-Pierre, Cecillia Lui, Sean Kearney, Enoch Yeung, Henry Halperin, Chun Woo Choi, Joseph Katz
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2021, 143(2): 021008.
Paper No: BIO-20-1256
https://doi.org/10.1115/1.4048424
Published Online: October 30, 2020
View Articletitled, Time-Resolved Echo-Particle Image/Tracking Velocimetry Measurement of Interactions Between Native Cardiac Output and Veno-Arterial ECMO Flows
Open the PDF for Time-Resolved Echo-Particle Image/Tracking Velocimetry Measurement of Interactions Between Native Cardiac Output and Veno-Arterial ECMO Flows in another window
Topics: Bubbles, Echoes, Flow (Dynamics), Valves, Particulate matter, Ultrasound
Journal Articles

Lymphatic Valves Separate Lymph Flow Into a Central Stream and a Slow-Moving Peri-Valvular Milieu

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Akshay Pujari, Alexander F. Smith, Joshua D. Hall, Patrick Mei, Kin Chau, Duy T. Nguyen, Daniel T. Sweet, Juan M. Jiménez
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2020, 142(10): 100805.
Paper No: BIO-20-1021
https://doi.org/10.1115/1.4048028
Published Online: August 31, 2020
View Articletitled, Lymphatic Valves Separate Lymph Flow Into a Central Stream and a Slow-Moving Peri-Valvular Milieu
Open the PDF for Lymphatic Valves Separate Lymph Flow Into a Central Stream and a Slow-Moving Peri-Valvular Milieu in another window
Topics: Flow (Dynamics), Valves, Vessels, Particulate matter
Journal Articles

Acoustic Cell Separation Based on Density and Mechanical Properties

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Yuliang Xie, Zhangming Mao, Hunter Bachman, Peng Li, Peiran Zhang, Liqiang Ren, Mengxi Wu, Tony Jun Huang
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2020, 142(3): 031005.
Paper No: BIO-19-1496
https://doi.org/10.1115/1.4046180
Published Online: February 28, 2020
View Articletitled, Acoustic Cell Separation Based on Density and Mechanical Properties
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Topics: Acoustics, Density, Mechanical properties, Particulate matter, Separation (Technology), Pressure
Includes: Supplementary data
Journal Articles

A Dynamic Escape Problem of Molecular Motors

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Dean Culver, Bryan Glaz, Samuel Stanton
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. May 2020, 142(5): 051004.
Paper No: BIO-18-1527
https://doi.org/10.1115/1.4044580
Published Online: January 20, 2020
View Articletitled, A Dynamic Escape Problem of Molecular Motors
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Topics: Bridges (Structures), Dimensions, Molecular motors, Motors, Muscle, Particulate matter, Potential energy, Design, Proteins, Dynamics (Mechanics)