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Journal Articles

Lamina Cribrosa Hypoxia Sensitivity to Variations of Anatomy and Vascular Factors

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Yuankai Lu, Yi Hua, Po-Yi Lee, Andrew Theophanous, Shaharoz Tahir, Qi Tian, Ian A. Sigal
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2025, 147(8): 081002.
Paper No: BIO-24-1228
https://doi.org/10.1115/1.4068577
Published Online: June 11, 2025
View Articletitled, Lamina Cribrosa Hypoxia Sensitivity to Variations of Anatomy and Vascular Factors
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Topics: Hemodynamics, Oxygen, Pressure, Vessels, Biological tissues, Blood, Anatomy
Includes: Supplementary data
Journal Articles

Bubbler System Design for Regulating Media Oxygen Levels in an Open Testing Environment

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Margaret H. Capalbo, Spencer E. Szczesny
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. August 2025, 147(8): 084503.
Paper No: BIO-25-1002
https://doi.org/10.1115/1.4068635
Published Online: June 9, 2025
View Articletitled, Bubbler System Design for Regulating Media Oxygen Levels in an Open Testing Environment
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Topics: Design, Flow (Dynamics), Nitrogen, Optimization, Oxygen, Pumps, Testing, Tendons
Includes: Supplementary data
Journal Articles

Computational Analysis of Flow and Transport Suggests Reduced Oxygen Levels Within Intracranial Aneurysms, Especially in Individuals With Sickle-Cell Disease

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Marisa S. Bazzi, Hadi Wiputra, David K. Wood, Victor H. Barocas
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2025, 147(2): 021006.
Paper No: BIO-23-1376
https://doi.org/10.1115/1.4067323
Published Online: January 3, 2025
View Articletitled, Computational Analysis of Flow and Transport Suggests Reduced Oxygen Levels Within Intracranial Aneurysms, Especially in Individuals With Sickle-Cell Disease
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Topics: Aneurysms, Oxygen, Vessels, Blood, Blood flow, Flow (Dynamics)
Includes: Supplementary data
Journal Articles

Computational Pulsatile Flow and Efficiency Analysis of Biocompatible Microfluidic Artificial Lungs for Different Fiber Configurations

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Ahmet Yusuf Asiltürk, Kunt Atalık
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2024, 146(8): 081002.
Paper No: BIO-23-1143
https://doi.org/10.1115/1.4064793
Published Online: March 21, 2024
View Articletitled, Computational Pulsatile Flow and Efficiency Analysis of Biocompatible Microfluidic Artificial Lungs for Different Fiber Configurations
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Topics: Artificial lungs, Biocompatibility, Blood, Fibers, Flow (Dynamics), Membranes, Microfluidics, Oxygen, Pressure drop, Pulsatile flow
Journal Articles

Optimization of Oxygen Delivery Within Hydrogels

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Sophia M. Mavris, Laura M. Hansen
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2021, 143(10): 101004.
Paper No: BIO-21-1045
https://doi.org/10.1115/1.4051119
Published Online: June 16, 2021
View Articletitled, Optimization of Oxygen Delivery Within Hydrogels
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Topics: Hydrogels, Oxygen, Diffusion (Physics)
Journal Articles

An Efficient Assisted Bidirectional Glenn Design With Lowered Superior Vena Cava Pressure for Stage-One Single Ventricle Patients

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Dongjie Jia, Matthew Peroni, Tigran Khalapyan, Mahdi Esmaily
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2021, 143(7): 071008.
Paper No: BIO-20-1267
https://doi.org/10.1115/1.4050170
Published Online: April 7, 2021
View Articletitled, An Efficient Assisted Bidirectional Glenn Design With Lowered Superior Vena Cava Pressure for Stage-One Single Ventricle Patients
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Topics: Bathythermographs, Blood, Flow (Dynamics), Oxygen, Pressure, Simulation, Design, Nozzles
Journal Articles

The Story of Wall Shear Stress in Coronary Artery Atherosclerosis: Biochemical Transport and Mechanotransduction

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Mostafa Mahmoudi, Ali Farghadan, Daniel R. McConnell, Alex J. Barker, Jolanda J. Wentzel, Matthew J. Budoff, Amirhossein Arzani
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2021, 143(4): 041002.
Paper No: BIO-20-1283
https://doi.org/10.1115/1.4049026
Published Online: December 14, 2020
View Articletitled, The Story of Wall Shear Stress in Coronary Artery Atherosclerosis: Biochemical Transport and Mechanotransduction
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Topics: Atherosclerosis, Coronary arteries, Oxygen, Proteins, Shear stress, Density, Endothelial cells, Permeability, Diseases, Computational fluid dynamics
Journal Articles

Simulation of Airflow in an Idealized Emphysematous Human Acinus

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Amitvikram Dutta, Dragos M. Vasilescu, James C. Hogg, A. B. Phillion, J. R. Brinkerhoff
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2018, 140(7): 071001.
Paper No: BIO-17-1253
https://doi.org/10.1115/1.4039680
Published Online: April 19, 2018
View Articletitled, Simulation of Airflow in an Idealized Emphysematous Human Acinus
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Topics: Air flow, Ducts, Flow (Dynamics), Oxygen, Simulation, Lung
Journal Articles

Mathematical Model for Tissue-Level Hypoxic Response in Microfluidic Environment

Open Access
Adnan Morshed, Prashanta Dutta
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2018, 140(1): 011009.
Paper No: BIO-17-1090
https://doi.org/10.1115/1.4037915
Published Online: November 9, 2017
View Articletitled, Mathematical Model for Tissue-Level Hypoxic Response in Microfluidic Environment
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Topics: Biological tissues, Microfluidics, Oxygen, Cancer
Includes: Supplementary data
Journal Articles

Simulations Reveal Adverse Hemodynamics in Patients With Multiple Systemic to Pulmonary Shunts

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Mahdi Esmaily-Moghadam, Bari Murtuza, Tain-Yen Hsia, Alison Marsden
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2015, 137(3): 031001.
Paper No: BIO-13-1320
https://doi.org/10.1115/1.4029429
Published Online: March 1, 2015
View Articletitled, Simulations Reveal Adverse Hemodynamics in Patients With Multiple Systemic to Pulmonary Shunts
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Topics: Bathythermographs, Flow (Dynamics), Hemodynamics, Simulation, Shear stress, Thrombosis, Oxygen, Fluid structure interaction, Engineering simulation
Journal Articles

Evaluation of the Effective Diffusivity of a Freeform Fabricated Scaffold Using Computational Simulation

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Jin Woo Jung, Hee-Gyeong Yi, Tae-Yun Kang, Woon-Jae Yong, Songwan Jin, Won-Soo Yun, Dong-Woo Cho
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. August 2013, 135(8): 084501.
Paper No: BIO-12-1208
https://doi.org/10.1115/1.4024570
Published Online: June 12, 2013
View Articletitled, Evaluation of the Effective Diffusivity of a Freeform Fabricated Scaffold Using Computational Simulation
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Topics: Diffusion (Physics), Oxygen, Simulation, Finite element analysis
Journal Articles

The Role of Collagen Synthesis in Ventricular and Vascular Adaptation to Hypoxic Pulmonary Hypertension

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David Schreier, Timothy Hacker, Gouqing Song, Naomi Chesler
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2013, 135(2): 021018.
Paper No: BIO-12-1576
https://doi.org/10.1115/1.4023480
Published Online: February 7, 2013
View Articletitled, The Role of Collagen Synthesis in Ventricular and Vascular Adaptation to Hypoxic Pulmonary Hypertension
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Topics: Blood, Hemodynamics, Lung, Pressure, Ventilation, Oxygen, Pulmonary artery, Biological tissues
Journal Articles

Effects of Myocardial Infarction on the Distribution and Transport of Nutrients and Oxygen in Porcine Myocardium

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Bryce H. Davis, Yoshihisa Morimoto, Chris Sample, Kevin Olbrich, Holly A. Leddy, Farshid Guilak, Doris A. Taylor
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. October 2012, 134(10): 101005.
https://doi.org/10.1115/1.4007455
Published Online: October 1, 2012
View Articletitled, Effects of Myocardial Infarction on the Distribution and Transport of Nutrients and Oxygen in Porcine Myocardium
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Topics: Diffusion (Physics), Glucose, Myocardium, Oxygen, Biological tissues, Patient treatment
Journal Articles

Stretching Affects Intracellular Oxygen Levels: Three-Dimensional Multiphysics Studies

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Efrat Leopold, Amit Gefen
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. June 2012, 134(6): 064501.
https://doi.org/10.1115/1.4006813
Published Online: June 8, 2012
View Articletitled, Stretching Affects Intracellular Oxygen Levels: Three-Dimensional Multiphysics Studies
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Topics: Deformation, Diffusion (Physics), Modeling, Oxygen, Temperature, Simulation, Cellular mechanics, Finite element analysis, Geometry
Journal Articles

Optimization of Shunt Placement for the Norwood Surgery Using Multi-Domain Modeling

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Mahdi Esmaily Moghadam, Francesco Migliavacca, Irene E. Vignon-Clementel, Tain-Yen Hsia, Alison L. Marsden, Modeling of Congenital Hearts Alliance (MOCHA) Investigators
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. May 2012, 134(5): 051002.
https://doi.org/10.1115/1.4006814
Published Online: May 25, 2012
View Articletitled, Optimization of Shunt Placement for the Norwood Surgery Using Multi-Domain Modeling
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Topics: Design, Flow (Dynamics), Geometry, Optimization, Oxygen, Surgery, Anatomy, Blood flow, Pressure, Coronary arteries
Journal Articles

Effect of Pore Architecture on Oxygen Diffusion in 3D Scaffolds for Tissue Engineering

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Geunseon Ahn, Jeong Hun Park, Taeyun Kang, Jin Woo Lee, Hyun-Wook Kang, Dong-Woo Cho
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. October 2010, 132(10): 104506.
https://doi.org/10.1115/1.4002429
Published Online: September 28, 2010
View Articletitled, Effect of Pore Architecture on Oxygen Diffusion in 3D Scaffolds for Tissue Engineering
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Topics: Diffusion (Physics), Numerical analysis, Oxygen
Journal Articles

Oxygen Transport in Brain Tissue

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Kazuto Masamoto, Kazuo Tanishita
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technology Review
J Biomech Eng. July 2009, 131(7): 074002.
https://doi.org/10.1115/1.3184694
Published Online: July 27, 2009
View Articletitled, Oxygen Transport in Brain Tissue
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Topics: Biological tissues, Blood flow, Brain, Oxygen
Journal Articles

Strain-Dependent Oxygen Diffusivity in Bovine Annulus Fibrosus

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T.-Y. Yuan, A. R. Jackson, C.-Y. Huang, W. Y. Gu
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. July 2009, 131(7): 074503.
https://doi.org/10.1115/1.3127254
Published Online: June 4, 2009
View Articletitled, Strain-Dependent Oxygen Diffusivity in Bovine Annulus Fibrosus
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Topics: Compression, Oxygen, Annulus, Biological tissues, Diffusion (Physics), Intervertebral discs
Journal Articles

Development and Validation of a System for the Growth of Cells and Tissues Under Intermittent Hydrostatic Pressure

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Troy J. Eggum, Christopher J. Hunter
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. December 2008, 130(6): 064501.
https://doi.org/10.1115/1.2979864
Published Online: October 10, 2008
View Articletitled, Development and Validation of a System for the Growth of Cells and Tissues Under Intermittent Hydrostatic Pressure
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Topics: Biological tissues, Bioreactors, Design, Glucose, Hydrostatic pressure, Oxygen, Pressure, Stem cells, Pressure testing, Intervertebral discs
Journal Articles

Pulsatile Flow and Oxygen Transport Past Cylindrical Fiber Arrays for an Artificial Lung: Computational and Experimental Studies

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Jennifer R. Zierenberg, Hideki Fujioka, Keith E. Cook, James B. Grotberg
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. June 2008, 130(3): 031019.
https://doi.org/10.1115/1.2907752
Published Online: May 9, 2008
View Articletitled, Pulsatile Flow and Oxygen Transport Past Cylindrical Fiber Arrays for an Artificial Lung: Computational and Experimental Studies
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Topics: Artificial lungs, Fibers, Flow (Dynamics), Oxygen, Pulsatile flow, Fluids, Pressure drop, Cylinders, Computer simulation