Cryosurgery is a rapidly developing discipline, alternative to conventional surgical techniques, used to destroy cancer cells by the action of low temperatures. Currently, the refrigeration is obtained via the adiabatic expansion of gases in probes used for surgeries, with the need of inherently dangerous pressurized vessels. The proposed innovative prototypal apparatus aims to reach the cryosurgical temperatures exploiting a closed-loop refrigeration system, avoiding the hazardous presence of pressurized vessels in the operating room. This study preliminarily examines the technical feasibility of the cryoablation with this machine focusing the attention on the cryoprobe design. Cryoprobe geometry and materials are assessed and the related heat transfer taking place during the cryoablation process is simulated with the aid of the computational fluid dynamics software ANSYS®Fluent. Parametric analyses are carried out varying the length of the collecting tubes and the inlet velocity of the cold carrier fluid in the cryoprobe. The values obtained for physical quantities such as the temperature reached in the treated tissue, the width of the obtained cold front, and the maximum pressure required for the cold carrier fluid are calculated and discussed in order to prove the effectiveness of the experimental apparatus and develop the machine further.
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January 2019
Research-Article
Numerical Simulation of the Heat Transfer in the Cryoprobe of an Innovative Apparatus for Cryosurgery
Barbara Bosio,
Barbara Bosio
Department of Civil, Chemical and
Environmental Engineering,
University of Genoa,
Via Opera Pia 15,
Genova 16145, Italy
e-mail: barbara.bosio@unige.it
Environmental Engineering,
University of Genoa,
Via Opera Pia 15,
Genova 16145, Italy
e-mail: barbara.bosio@unige.it
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Dario Bove,
Dario Bove
Faculty of Sciences and Technology,
Free University of Bozen-Bolzano,
Piazza Università 5,
Bolzano 39100, Italy
e-mail: ing.dariobove@gmail.com
Free University of Bozen-Bolzano,
Piazza Università 5,
Bolzano 39100, Italy
e-mail: ing.dariobove@gmail.com
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Lorenzo Guidetti,
Lorenzo Guidetti
Department of Civil, Chemical and
Environmental Engineering,
University of Genoa,
Via Opera Pia 15,
Genova 16145, Italy
e-mail: lo.guidetti@yahoo.it
Environmental Engineering,
University of Genoa,
Via Opera Pia 15,
Genova 16145, Italy
e-mail: lo.guidetti@yahoo.it
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Elisabetta Arato
Elisabetta Arato
Department of Civil, Chemical and
Environmental Engineering,
University of Genoa,
Via Opera Pia 15,
Genova 16145, Italy
e-mail: elisabetta.arato@unige.it
Environmental Engineering,
University of Genoa,
Via Opera Pia 15,
Genova 16145, Italy
e-mail: elisabetta.arato@unige.it
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Barbara Bosio
Department of Civil, Chemical and
Environmental Engineering,
University of Genoa,
Via Opera Pia 15,
Genova 16145, Italy
e-mail: barbara.bosio@unige.it
Environmental Engineering,
University of Genoa,
Via Opera Pia 15,
Genova 16145, Italy
e-mail: barbara.bosio@unige.it
Dario Bove
Faculty of Sciences and Technology,
Free University of Bozen-Bolzano,
Piazza Università 5,
Bolzano 39100, Italy
e-mail: ing.dariobove@gmail.com
Free University of Bozen-Bolzano,
Piazza Università 5,
Bolzano 39100, Italy
e-mail: ing.dariobove@gmail.com
Lorenzo Guidetti
Department of Civil, Chemical and
Environmental Engineering,
University of Genoa,
Via Opera Pia 15,
Genova 16145, Italy
e-mail: lo.guidetti@yahoo.it
Environmental Engineering,
University of Genoa,
Via Opera Pia 15,
Genova 16145, Italy
e-mail: lo.guidetti@yahoo.it
Leopoldo Avalle
Elisabetta Arato
Department of Civil, Chemical and
Environmental Engineering,
University of Genoa,
Via Opera Pia 15,
Genova 16145, Italy
e-mail: elisabetta.arato@unige.it
Environmental Engineering,
University of Genoa,
Via Opera Pia 15,
Genova 16145, Italy
e-mail: elisabetta.arato@unige.it
1Corresponding author.
Manuscript received April 20, 2018; final manuscript received August 20, 2018; published online October 17, 2018. Assoc. Editor: Ram Devireddy.
J Biomech Eng. Jan 2019, 141(1): 011008 (11 pages)
Published Online: October 17, 2018
Article history
Received:
April 20, 2018
Revised:
August 20, 2018
Citation
Bosio, B., Bove, D., Guidetti, L., Avalle, L., and Arato, E. (October 17, 2018). "Numerical Simulation of the Heat Transfer in the Cryoprobe of an Innovative Apparatus for Cryosurgery." ASME. J Biomech Eng. January 2019; 141(1): 011008. https://doi.org/10.1115/1.4041526
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