Rapid flexion and extension of the neck may occur during scenarios associated with traumatic brain injury (TBI), and understanding the mechanical response of the common carotid artery (CCA) to longitudinal stretch may enhance understanding of contributing factors that may influence CCA vasospasm and exacerbate ischemic injury associated with TBI. Immature (4-week-old) porcine CCAs were tested under subcatastrophic (1.5 peak stretch ratio) cyclic loading at 3 Hz for 30 s. Under subcatastrophic cyclic longitudinal extension, the immature porcine CCA displays softening behavior. This softening can be represented by decreasing peak stress and increasing corner stretch values with an increasing number of loading cycles. This investigation is an important first step in the exploration of fatiguelike behavior in arterial tissue that may be subjected to repeated longitudinal loads.
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December 2016
Technical Briefs
Repeated Loading Behavior of Pediatric Porcine Common Carotid Arteries
Stephanie A. Pasquesi,
Stephanie A. Pasquesi
Department of Bioengineering,
University of Pennsylvania,
240 Skirkanich Hall,
210 South 33rd Street,
Philadelphia, PA 19104-6321
University of Pennsylvania,
240 Skirkanich Hall,
210 South 33rd Street,
Philadelphia, PA 19104-6321
Search for other works by this author on:
Yishan Liu,
Yishan Liu
Department of Bioengineering,
University of Pennsylvania,
240 Skirkanich Hall,
210 South 33rd Street,
Philadelphia, PA 19104-6321
University of Pennsylvania,
240 Skirkanich Hall,
210 South 33rd Street,
Philadelphia, PA 19104-6321
Search for other works by this author on:
Susan S. Margulies
Susan S. Margulies
Department of Bioengineering,
University of Pennsylvania,
240 Skirkanich Hall,
210 South 33rd Street,
Philadelphia, PA 19104-6321
e-mail: [email protected]
University of Pennsylvania,
240 Skirkanich Hall,
210 South 33rd Street,
Philadelphia, PA 19104-6321
e-mail: [email protected]
Search for other works by this author on:
Stephanie A. Pasquesi
Department of Bioengineering,
University of Pennsylvania,
240 Skirkanich Hall,
210 South 33rd Street,
Philadelphia, PA 19104-6321
University of Pennsylvania,
240 Skirkanich Hall,
210 South 33rd Street,
Philadelphia, PA 19104-6321
Yishan Liu
Department of Bioengineering,
University of Pennsylvania,
240 Skirkanich Hall,
210 South 33rd Street,
Philadelphia, PA 19104-6321
University of Pennsylvania,
240 Skirkanich Hall,
210 South 33rd Street,
Philadelphia, PA 19104-6321
Susan S. Margulies
Department of Bioengineering,
University of Pennsylvania,
240 Skirkanich Hall,
210 South 33rd Street,
Philadelphia, PA 19104-6321
e-mail: [email protected]
University of Pennsylvania,
240 Skirkanich Hall,
210 South 33rd Street,
Philadelphia, PA 19104-6321
e-mail: [email protected]
1Corresponding author.
Manuscript received January 4, 2016; final manuscript received June 5, 2016; published online November 3, 2016. Assoc. Editor: Barclay Morrison.
J Biomech Eng. Dec 2016, 138(12): 124502 (5 pages)
Published Online: November 3, 2016
Article history
Received:
January 4, 2016
Revised:
June 5, 2016
Citation
Pasquesi, S. A., Liu, Y., and Margulies, S. S. (November 3, 2016). "Repeated Loading Behavior of Pediatric Porcine Common Carotid Arteries." ASME. J Biomech Eng. December 2016; 138(12): 124502. https://doi.org/10.1115/1.4033883
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