The Mathematical Biosciences Institute at The Ohio State University hosted a week-long workshop on tissue engineering and regenerative medicine (TERM) from April 30 to May 4, 2012. The workshop brought together 28 speakers from an array of disciplines, with an overarching goal of contributing to the development of mathematical and computational approaches that would allow one to rigorously understand, predict, and control complex biological processes relevant to TERM. Abstracts of the presentations, along with links to videos of many of the talks, can be found at http://mbi.osu.edu/2011/terabstracts.html. One theme that was common to many of these talks was a focus on biomechanical aspects of cell-matrix interactions. This special issue includes ten articles on cell-matrix interactions that were based on these talks.

Cells adhere to and dynamically interact with the extracellular matrix (ECM) through various adhesion complexes that are coupled to the contractile machinery of...

References

References
1.
McLeod
,
C.
,
Higgins
,
J.
,
Miroshnikova
,
Y.
,
Liu
,
R.
,
Garrett
,
A.
, and
Sarang-Sieminski
,
A. L.
, “
Microscopic Matrix Remodeling Precedes Endothelial Morphological Changes During Capillary Morphogenesis
,”
ASME J. Biomech. Eng.
,
135
(
7
), p.
071002
.10.1115/1.4023984
2.
Reinhardt
,
J. W.
,
Krakauer
,
D. A.
, and
Gooch
,
K. J.
, “
Complex Matrix Remodeling and Durotaxis Can Emerge From Simple Rules for Cell-Matrix Interaction in Agent-Based Models
,”
ASME J. Biomech. Eng.
,
135
(
7
), p.
071003
.10.1115/1.4024463
3.
Aghvami
,
M.
,
Barocas
,
V. H.
, and
Sander
,
E. A.
, “
Multiscale Mechanical Simulations of Cell Compacted Collagen Gels
,”
ASME J. Biomech. Eng.
,
135
(
7
), p.
071004
. 10.1115/1.4024460
4.
Sander
,
L. M.
, “
Alignment Localization in Non-linear Biological Media
,”
ASME J. Biomech. Eng.
,
135
(
7
), p.
071006
. 10.1115/1.4024199
5.
Yang
,
X.
,
Sun
,
Y.
, and
Wang
,
Q.
, “
Phase Field Approach for Multicellular Aggregate Fusion in Biofabrication
,”
ASME J. Biomech. Eng.
,
135
(
7
), p.
071005
. 10.1115/1.4024139
6.
Dallon
,
J. C.
,
Scott
,
M.
, and
Smith
,
W. V.
, “
A Force-Based Model of Individual Cell Migration With Discrete Attachment Sites and Random Switching Terms
,”
ASME J. Biomech. Eng.
,
135
(
7
), p.
071008
. 10.1115/1.4023987
7.
Lai
,
V. K.
,
Hadi
,
M. F.
,
Tranquillo
,
R. T.
, and
Barocas
,
V. H.
, “
A Multiscale Approach to Modeling the Passive Mechanical Contribution of Cells in Tissues
,”
ASME J. Biomech. Eng.
,
135
(
7
), p.
071007
.10.1115/1.4024350
8.
Zielinski
,
R.
,
Mihai
,
C.
,
Kniss
,
D.
, and
Ghadiali
,
S. N.
, “
Finite Element Analysis of Traction Force Microscopy: Influence of Cell Mechanics, Adhesion and Morphology
,”
ASME J. Biomech. Eng.
,
135
(
7
), p.
071009
. 10.1115/1.4024467
9.
Fata
,
B.
,
Gottlieb
,
D.
,
Mayer
,
J. E.
, and
Sacks
,
M. S.
, “
Estimated in vivo Postnatal Surface Growth Patterns of the Ovine Main Pulmonary Artery and Ascending Aorta
,”
ASME J. Biomech. Eng.
,
135
(
7
), p.
071010
. 10.1115/1.4024619
10.
Sullivan
,
K. E.
, and
Black
III,
L. D.
, “
The Role of Cardiac Fibroblasts in Extracellular Matrix Mediated Signaling During Normal and Pathological Cardiac Development
,”
ASME J. Biomech. Eng.
,
135
(
7
), p.
071001
. 10.1115/1.4024349
You do not currently have access to this content.