Dynamic mechanical properties of placenta tissue are needed to develop computational models of pregnant occupants for use in designing restraint systems that protect the fetus and mother. Tests were performed on 21 samples obtained from five human placentas at a rate of 1200 %/s using a set of custom designed thermoelectrically cooled clamps. Approximately half of the samples from all five subjects were tested within 48 h of delivery. The remaining samples were frozen for 5–7 days and then thawed before testing. True failure stresses and strains were not significantly different between fresh and frozen samples (p-value = 0.858 and 0.551, respectively), suggesting that soft tissue may be stored frozen up to a week without adversely affecting dynamic material response.
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kklinich@umich.edu
carlmill@umich.edu
jwhu@umich.edu
giseli.moreno@gmail.com
pearlman@med.umich.edu
lws@umich.edu
jrupp@umich.edu
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March 2012
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Effect of Frozen Storage on Dynamic Tensile Properties of Human Placenta
Kathleen D. Klinich,
Kathleen D. Klinich
Assistant Research Scientist
Transportation Research Institute,
kklinich@umich.edu
University of Michigan
, 2901 Baxter Road, Ann Arbor, MI 48109
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Carl S. Miller,
Carl S. Miller
Senior Engineer in Research
Transportation Research Institute,
carlmill@umich.edu
University of Michigan
, 2901 Baxter Road, Ann Arbor, MI 48109
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Jingwen Hu,
Jingwen Hu
Assistant Research Scientist
Transportation Research Institute,
jwhu@umich.edu
University of Michigan
, 2901 Baxter Road, Ann Arbor, MI 48109
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Giseli M. Nazmi,
giseli.moreno@gmail.com
Giseli M. Nazmi
Research Associate
University of Michigan Hospital and Health Centers
1500 E. Med Center Drive, L4000 Women’s Hospital, Ann Arbor, MI 48109-0276
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Mark D. Pearlman,
pearlman@med.umich.edu
Mark D. Pearlman
Associate Chief of Clinical Affairs
University of Michigan Hospital and Health Centers;
S Jan Behrman Professor and Service Chief,Department of Ob/Gyn, 1500 E. Med Center Drive, L4000 Women’s Hospital,Ann Arbor, MI 48109-0276
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Lawrence W. Schneider,
Lawrence W. Schneider
Research Professor,
Transportation Research Institute,
lws@umich.edu
University of Michigan;
Research Professor of Biomedical Engineering,College of Engineering, 2901 Baxter Road, Ann Arbor, MI 48109
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Jonathan D. Rupp
Jonathan D. Rupp
Research Associate Professor
Transportation Research Institute,
jrupp@umich.edu
University of Michigan;
Research Associate Professor of Emergency Medicine, University of Michigan Medical School;
Research Associate Professor of Biomedical Engineering, University of Michigan College of Engineering
, 2901 Baxter Road, Ann Arbor, MI 48109
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Kathleen D. Klinich
Assistant Research Scientist
Transportation Research Institute,
University of Michigan
, 2901 Baxter Road, Ann Arbor, MI 48109kklinich@umich.edu
Carl S. Miller
Senior Engineer in Research
Transportation Research Institute,
University of Michigan
, 2901 Baxter Road, Ann Arbor, MI 48109carlmill@umich.edu
Jingwen Hu
Assistant Research Scientist
Transportation Research Institute,
University of Michigan
, 2901 Baxter Road, Ann Arbor, MI 48109jwhu@umich.edu
Giseli M. Nazmi
Research Associate
University of Michigan Hospital and Health Centers
1500 E. Med Center Drive, L4000 Women’s Hospital, Ann Arbor, MI 48109-0276giseli.moreno@gmail.com
Mark D. Pearlman
Associate Chief of Clinical Affairs
University of Michigan Hospital and Health Centers;
S Jan Behrman Professor and Service Chief,Department of Ob/Gyn, 1500 E. Med Center Drive, L4000 Women’s Hospital,Ann Arbor, MI 48109-0276pearlman@med.umich.edu
Lawrence W. Schneider
Research Professor,
Transportation Research Institute,
University of Michigan;
Research Professor of Biomedical Engineering,College of Engineering, 2901 Baxter Road, Ann Arbor, MI 48109lws@umich.edu
Jonathan D. Rupp
Research Associate Professor
Transportation Research Institute,
University of Michigan;
Research Associate Professor of Emergency Medicine, University of Michigan Medical School;
Research Associate Professor of Biomedical Engineering, University of Michigan College of Engineering
, 2901 Baxter Road, Ann Arbor, MI 48109jrupp@umich.edu
J Biomech Eng. Mar 2012, 134(3): 034501 (4 pages)
Published Online: March 19, 2012
Article history
Received:
December 14, 2011
Revised:
January 9, 2012
Accepted:
January 11, 2012
Posted:
February 13, 2012
Published:
March 16, 2012
Online:
March 19, 2012
Citation
Klinich, K. D., Miller, C. S., Hu, J., Nazmi, G. M., Pearlman, M. D., Schneider, L. W., and Rupp, J. D. (March 19, 2012). "Effect of Frozen Storage on Dynamic Tensile Properties of Human Placenta." ASME. J Biomech Eng. March 2012; 134(3): 034501. https://doi.org/10.1115/1.4006025
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