Background. Computational fluid dynamics (CFD) simulations using medical-image-based anatomical vascular geometry are now gaining clinical relevance. This study aimed at validating the CFD methodology for studying cerebral aneurysms by using particle image velocimetry (PIV) measurements, with a focus on the effects of small geometric variations in aneurysm models on the flow dynamics obtained with CFD. Method of Approach. An experimental phantom was fabricated out of silicone elastomer to best mimic a spherical aneurysm model. PIV measurements were obtained from the phantom and compared with the CFD results from an ideal spherical aneurysm model (S1). These measurements were also compared with CFD results, based on the geometry reconstructed from three-dimensional images of the experimental phantom. We further performed CFD analysis on two geometric variations, S2 and S3, of the phantom to investigate the effects of small geometric variations on the aneurysmal flow field. Results. We found poor agreement between the CFD results from the ideal spherical aneurysm model and the PIV measurements from the phantom, including inconsistent secondary flow patterns. The CFD results based on the actual phantom geometry, however, matched well with the PIV measurements. CFD of models S2 and S3 produced qualitatively similar flow fields to that of the phantom but quantitatively significant changes in key hemodynamic parameters such as vorticity, positive circulation, and wall shear stress. Conclusion. CFD simulation results can closely match experimental measurements as long as both are performed on the same model geometry. Small geometric variations on the aneurysm model can significantly alter the flow-field and key hemodynamic parameters. Since medical images are subjected to geometric uncertainties, image-based patient-specific CFD results must be carefully scrutinized before providing clinical feedback.
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e-mail: huimeng@eng.buffalo.edu
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December 2006
Technical Papers
Validation of CFD Simulations of Cerebral Aneurysms With Implication of Geometric Variations
Yiemeng Hoi,
Yiemeng Hoi
Department of Mechanical and Aerospace Engineering,
University at Buffalo
, Buffalo, NY 14260 and Toshiba Stroke Research Center, University at Buffalo
, Buffalo, NY 14260
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Scott H. Woodward,
Scott H. Woodward
Department of Mechanical and Aerospace Engineering,
University at Buffalo
, Buffalo, NY 14260 and Toshiba Stroke Research Center, University at Buffalo
, Buffalo, NY 14260
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Minsuok Kim,
Minsuok Kim
Department of Mechanical and Aerospace Engineering,
University at Buffalo
, Buffalo, NY 14260 and Toshiba Stroke Research Center, University at Buffalo
, Buffalo, NY 14260
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Dale B. Taulbee,
Dale B. Taulbee
Department of Mechanical and Aerospace Engineering,
University at Buffalo
, Buffalo, NY 14260
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Hui Meng
Hui Meng
Department of Mechanical and Aerospace Engineering,
e-mail: huimeng@eng.buffalo.edu
University at Buffalo
, Buffalo, NY 14260; Toshiba Stroke Research Center, University at Buffalo
, Buffalo, NY 14260; and Department of Neurosurgery, University at Buffalo
, Buffalo, NY 14260
Search for other works by this author on:
Yiemeng Hoi
Department of Mechanical and Aerospace Engineering,
University at Buffalo
, Buffalo, NY 14260 and Toshiba Stroke Research Center, University at Buffalo
, Buffalo, NY 14260
Scott H. Woodward
Department of Mechanical and Aerospace Engineering,
University at Buffalo
, Buffalo, NY 14260 and Toshiba Stroke Research Center, University at Buffalo
, Buffalo, NY 14260
Minsuok Kim
Department of Mechanical and Aerospace Engineering,
University at Buffalo
, Buffalo, NY 14260 and Toshiba Stroke Research Center, University at Buffalo
, Buffalo, NY 14260
Dale B. Taulbee
Department of Mechanical and Aerospace Engineering,
University at Buffalo
, Buffalo, NY 14260
Hui Meng
Department of Mechanical and Aerospace Engineering,
University at Buffalo
, Buffalo, NY 14260; Toshiba Stroke Research Center, University at Buffalo
, Buffalo, NY 14260; and Department of Neurosurgery, University at Buffalo
, Buffalo, NY 14260e-mail: huimeng@eng.buffalo.edu
J Biomech Eng. Dec 2006, 128(6): 844-851 (8 pages)
Published Online: June 15, 2006
Article history
Received:
September 27, 2005
Revised:
June 15, 2006
Citation
Hoi, Y., Woodward, S. H., Kim, M., Taulbee, D. B., and Meng, H. (June 15, 2006). "Validation of CFD Simulations of Cerebral Aneurysms With Implication of Geometric Variations." ASME. J Biomech Eng. December 2006; 128(6): 844–851. https://doi.org/10.1115/1.2354209
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