Computational investigations of flow mixing and oxygen transfer characteristics in an intravenous membrane oxygenator (IMO) are performed by direct numerical simulations of the conservation of mass, momentum, and species equations. Three-dimensional computational models are developed to investigate flow-mixing and oxygen-transfer characteristics for stationary and pulsating balloons, using the spectral element method. For a stationary balloon, the effect of the fiber placement within the fiber bundle and the number of fiber rings is investigated. In a pulsating balloon, the flow mixing characteristics are determined and the oxygen transfer rate is evaluated. For a stationary balloon, numerical simulations show two well-defined flow patterns that depend on the region of the IMO device. Successive increases of the Reynolds number raise the longitudinal velocity without creating secondary flow. This characteristic is not affected by staggered or non-staggered fiber placement within the fiber bundle. For a pulsating balloon, the flow mixing is enhanced by generating a three-dimensional time-dependent flow characterized by oscillatory radial, pulsatile longitudinal, and both oscillatory and random tangential velocities. This three-dimensional flow increases the flow mixing due to an active time-dependent secondary flow, particularly around the fibers. Analytical models show the fiber bundle placement effect on the pressure gradient and flow pattern. The oxygen transport from the fiber surface to the mean flow is due to a dominant radial diffusion mechanism, for the stationary balloon. The oxygen transfer rate reaches an asymptotic behavior at relatively low Reynolds numbers. For a pulsating balloon, the time-dependent oxygen-concentration field resembles the oscillatory and wavy nature of the time-dependent flow. Sherwood number evaluations demonstrate that balloon pulsations enhance the oxygen transfer rate, even for smaller flow rates.
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June 2005
Technical Papers
Flow Mixing Enhancement from Balloon Pulsations in an Intravenous Oxygenator
Amador M. Guzmán,
Amador M. Guzmán
Departamento de Ingeniería Mecánica
Universidad de Santiago de ChileAlameda 3363, Estación Central Santiago, Chile
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Rodrigo A. Escobar,
Rodrigo A. Escobar
Institute for Complex Engineered Systems, Departments of Mechanical Engineering and Biomedical Engineering,
Carnegie Mellon University
, 5000 Forbes Ave, Pittsburgh, PA 15213
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Cristina H. Amon
Cristina H. Amon
Institute for Complex Engineered Systems, Departments of Mechanical Engineering and Biomedical Engineering,
Carnegie Mellon University
, 5000 Forbes Ave, Pittsburgh, PA 15213
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Amador M. Guzmán
Departamento de Ingeniería Mecánica
Universidad de Santiago de ChileAlameda 3363, Estación Central Santiago, Chile
Rodrigo A. Escobar
Institute for Complex Engineered Systems, Departments of Mechanical Engineering and Biomedical Engineering,
Carnegie Mellon University
, 5000 Forbes Ave, Pittsburgh, PA 15213
Cristina H. Amon
Institute for Complex Engineered Systems, Departments of Mechanical Engineering and Biomedical Engineering,
Carnegie Mellon University
, 5000 Forbes Ave, Pittsburgh, PA 15213J Biomech Eng. Jun 2005, 127(3): 400-415 (16 pages)
Published Online: March 2, 2004
Article history
Received:
July 15, 2002
Revised:
March 2, 2004
Citation
Guzmán, A. M., Escobar, R. A., and Amon, C. H. (March 2, 2004). "Flow Mixing Enhancement from Balloon Pulsations in an Intravenous Oxygenator." ASME. J Biomech Eng. June 2005; 127(3): 400–415. https://doi.org/10.1115/1.1894260
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