Subablative thermotherapy is frequently used for the treatment of joint instability related diseases. In this therapy, mechanically deformed collagenous tissues are thermally shrunk and the stability of the tissue is re-established. In this research, the thermal damage fields generated by three different clinical heating modalities (monopolar and bipolar radio frequency and Ho:YAG laser) are compared numerically using finite element analysis. The heating rate dependent denaturation characteristics of collagenous tissues are incorporated into the model using experimental data from in vitro experimentation with rabbit patellar tendons. It is shown that there are significant differences among the thermal damage profiles created by these modalities, explaining the main reason for the discrepancies reported in the literature in terms of the efficacy and safety of each modality. In the complementary paper, the accuracy of the model presented here is verified by in vitro experimentation with a model collagenous tissue and by quantifying the denaturation-induced birefringence change using Optical Coherence Tomography and Magnetic Resonance Imaging.
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February 2005
Technical Papers
Thermal Damage Prediction for Collagenous Tissues Part I: A Clinically Relevant Numerical Simulation Incorporating Heating Rate Dependent Denaturation*
Alptekin Aksan,
Alptekin Aksan
Center for Engineering in Medicine and Department of Surgical Services, Massachusetts General Hospital, Harvard Medical School, and Shriners Hospital for Children, Boston, MA 02114
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John J. McGrath,
John J. McGrath
Aerospace and Mechanical Engineering Department, University of Arizona, Tucson, AZ 85721
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David S. Nielubowicz,, Jr.
David S. Nielubowicz,, Jr.
Pontiac Structural Durability Laboratories, General Motors Corporation, Pontiac, MI 48341
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Alptekin Aksan
11
Center for Engineering in Medicine and Department of Surgical Services, Massachusetts General Hospital, Harvard Medical School, and Shriners Hospital for Children, Boston, MA 02114
John J. McGrath
Aerospace and Mechanical Engineering Department, University of Arizona, Tucson, AZ 85721
David S. Nielubowicz,, Jr.
Pontiac Structural Durability Laboratories, General Motors Corporation, Pontiac, MI 48341
Contributed by the Bioengineering Division for publication in the JOURNAL OF BIOMECHANICAL ENGINEERING. Manuscript received by the Bioengineering Division February 29, 2004; revision received August 9, 2004. Associate Editor: Elaine P. Scott.
J Biomech Eng. Feb 2005, 127(1): 85-97 (13 pages)
Published Online: March 8, 2005
Article history
Received:
February 29, 2004
Revised:
August 9, 2004
Online:
March 8, 2005
Citation
Aksan, A., McGrath, J. J., and Nielubowicz, , D. S., Jr. (March 8, 2005). "Thermal Damage Prediction for Collagenous Tissues Part I: A Clinically Relevant Numerical Simulation Incorporating Heating Rate Dependent Denaturation." ASME. J Biomech Eng. February 2005; 127(1): 85–97. https://doi.org/10.1115/1.1835355
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