The left ventricular ejection fraction (LVEF) is an important clinical indicator of the cardiac function and long-term outcome for patients with coronary artery disease. A biomechanical model of the left ventricle was developed to quantitatively predict post-revascularization LVEF based on noninvasive magnetic resonance imaging. The myocardium was categorized into normal, hibernating, and infarcted regions from the ventricular short-axis images. Assuming that hibernating tissue would potentially regain contractility after revascularization, the expected maximum post-revascularization LVEF was calculated for four patients with chronic left ventricular dysfunction. The predictions were within three ejection fraction points of the follow-up LVEFs. This model may be useful to estimate the outcome and efficacy of revascularization plans.
A Left Ventricle Model to Predict Post-Revascularization Ejection Fraction Based on Cine Magnetic Resonance Images
Contributed by the Bioengineering Division for publication in the JOURNAL OF BIOMECHANICAL ENGINEERING. Manuscript received by the Bioengineering Division July 25, 2000; revised manuscript received September 17, 2001. Associate Editor: James E. Moore, Jr.
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Han, H., Oshinski, J. N., Ku, D. N., and Pettigrew, R. I. (September 17, 2001). "A Left Ventricle Model to Predict Post-Revascularization Ejection Fraction Based on Cine Magnetic Resonance Images ." ASME. J Biomech Eng. February 2002; 124(1): 52–55. https://doi.org/10.1115/1.1428555
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