The current trend in computational hemodynamics is to employ realistic models derived from ex vivo or in vivo imaging. Such studies typically produce a series of images from which the lumen boundaries must first be individually extracted (i.e., two-dimensional segmentation), and then serially reconstructed to produce the three-dimensional lumen surface geometry. In this paper, we present a rapid three-dimensional segmentation technique that combines these two steps, based on the idea of an expanding virtual balloon. This three-dimensional technique is demonstrated in application to finite element meshing and CFD modeling of flow in the carotid bifurcation of a normal volunteer imaged with black blood MRI. Wall shear stress patterns computed using a mesh generated with the three-dimensional technique agree well with those computed using a mesh generated from conventional two-dimensional segmentation and serial reconstruction. In addition to reducing the time required to extract the lumen surface from hours to minutes, our approach is easy to learn and use and requires minimal user intervention, which can potentially increase the accuracy and precision of quantitative and longitudinal studies of hemodynamics and vascular disease. [S0148-0731(00)00201-6]
Rapid Three-Dimensional Segmentation of the Carotid Bifurcation From Serial MR Images
Contributed by the Bioengineering Division of THE AMERICAN SOCIETY OF MECHANICAL ENGINEERS. Manuscript received by the Bioengineering Division March 31, 1999; revised manuscript received August 22, 1999. Associate Technical Editor: S. E. Rittgers.
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Ladak , H. M., Milner and , J. S., and Steinman, D. A. (August 22, 1999). "Rapid Three-Dimensional Segmentation of the Carotid Bifurcation From Serial MR Images." ASME. J Biomech Eng. February 2000; 122(1): 96–99. https://doi.org/10.1115/1.429646
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