Cryosurgery of the skin is a common treatment for both benign and malignant skin cancers. Monitoring the depth of the frozen lesion during cryosurgery, either by estimation based on the lateral spread of freeze at the skin surface or via thermocouples, may be inaccurate because of the heterogeneous nature of tissue. We describe an integrated cryosurgical probe and magnitude resonance imaging probe which we use to obtain high resolution MR images of skin, subcutaneous muscle and the frozen lesion during cryosurgery.

1.
Ackerman
J. J. H.
,
Grove
T. H.
,
Wong
G. G.
,
Gadian
D. G.
, and
Radda
G. K.
,
1980
, “
Mapping of Metabolites in Whole Animals by 31P NMR Using Surface Coils
,”
Nature
, Vol.
283
, pp.
167
170
.
2.
Bircher
A. J.
, and
Bu¨chner
S. A.
,
1991
, “
Blood Flow Response to Cryosurgery on Basal Cell Carcinomas
,”
Acta Derm Venereal (Stockh)
, Vol.
71
, pp.
531
533
.
3.
Dacho´w-Siwie´c
,
1990
, “
Treatment of Cryosurgery in the Premalignant and Benign Lesions of the Skin
,”
Clinics in Dermatology
, Vol.
8
, pp.
69
79
.
4.
Gage
A. A.
,
1990
, “
Cryosurgery of Advanced Tumors
,”
Clinics in Dermatology
, Vol.
8
, pp.
86
95
.
5.
Gage
A. A.
,
Augustynowicz
S.
,
Montes
M.
,
Caruana
J. A.
, and
Whalen
D. A.
,
1985
, “
Tissue Impedance and Temperature Measurements in Relation to Necrosis in Experimental Cryosurgery
,”
Cryobiology
, Vol.
22
, pp.
282
288
.
6.
Graham
G. F.
, and
Clark
L. C.
,
1990
, “
Statistical Analysis in Cryosurgery of Skin Cancer
,”
Clinics in Dermatology
, Vol.
8
, pp.
101
107
.
7.
Holman
W. L.
,
Kirklin
J. K.
,
Anderson
P. G.
, and
Pacifico
A. D.
,
1992
, “
Variation in Cryolesion Penetration Due to Probe Size and Tissue Thermal Conductivity
,”
Annals of Thoracic Surgery
, Vol.
53
, pp.
123
126
.
8.
Hoult
D. I.
, and
Richards
R. E.
,
1976
, “
The Signal-to-Noise Ratio of the Nuclear Magnetic Resonance Experiment
,”
Journal of Magnetic Resonance
, Vol.
24
, pp.
71
85
.
9.
Isoda
H.
,
1989
, “
Sequential MRI and CT Monitoring in Cryosurgery—An Experimental Study in Rats (Japanese)
,”
Nippon Igaku Hoshasen Gakkai Zasshi Nippon Acta Radiologica
, Vol.
49
, pp.
1499
1508
.
10.
Kuflik
A. S.
, and
Schwartz
R. A.
,
1992
, “
Lymphocytoma Cutis; A Series of Five Patients Successfully Treated with Cryosurgery
,”
Journal of the American Academy of Dermatology
, Vol.
26
, pp.
449
452
.
11.
Matsumoto
R.
,
Oshio
K.
, and
Jolesz
F. A.
,
1992
, “
Monitoring of Laser and Freezing-induced Ablation in the Liver with T1-weighted MR Imaging
,”
Journal of Magnetic Resonance Imaging
, Vol.
2
, pp.
555
562
.
12.
Morris, P. G., 1986, Nuclear Magnetic Resonance Imaging in Medicine and Biology, Chapter 2, New York, Oxford University Press.
13.
Rubinsky
B.
,
Gilbert
J. C.
,
Onik
G. M.
,
Roos
M. S.
,
Wong
S. T. S.
, and
Brennan
K. M.
,
1993
, “
Monitoring Cryosurgery in the Brain and in the Prostate with Proton NMR
,”
Cryobiology
, Vol.
30
, pp.
191
199
.
14.
Schenck, J. F., Hart, H. R. Jr., Foster, T. H., Edelstein, W. A., and Hussain, M. A., 1986, “High Resolution Magnetic Resonance Imaging Using Surface Coils,” Magnetic Resonance Annual, Kressel, H. Y., ed., New York, Raven Press, pp. 123–160.
15.
Schwaighofer
B. W.
,
Fruehwald
F. X. J.
,
Pohl-Markl
H.
,
Neuhold
A.
,
Wicke
L.
, and
Landrum
W. L.
,
1989
, “
MRI Evaluation of Pigmented Skin Tumors
,”
Investigative Radiology
, Vol.
24
, pp.
289
293
.
16.
Staewen
R. S.
,
Johnson
A. J.
,
Ross
B. D.
,
Parrish
T.
,
Merkle
H.
, and
Garwood
M.
,
1990
, “
3-D FLASH Imaging Using a Single Surface Coil and a New Adiabatic Pulse, BIR-4
,”
Investigative Radiology
, Vol.
25
, pp.
559
567
.
17.
Takahashi
M.
, and
Kohda
H.
,
1992
, “
Diagnostic Utility of Magnetic Resonance Imaging in Malignant Melanoma
,”
Journal of the American Academy of Dermatology
, Vol.
27
, pp.
51
54
.
18.
Tappero
J. W.
,
Berger
T. G.
,
Kaplan
L. D.
,
Volberding
P. A.
, and
Kahn
J. O.
,
1991
, “
Cryotherapy for Cutaneous Kaposi’s Sarcoma (KS) Associated with Acquired Immune Deficiency Syndrome (AIDS): A Phase II Trial
,”
Journal of Acquired Immune Deficiency Syndromes
, Vol.
4
, pp.
839
846
.
19.
Torre
D.
,
1980
, “
Cryosurgery of Basal Cell Carcinoma
,”
Journal of the American Academy of Dermatology
, Vol.
15
, pp.
917
929
.
20.
Torre
D.
,
1990
, “
Cryosurgical Instrumentation and Depth Dose Monitoring
,”
Clinics in Dermatology
, Vol.
8
, pp.
48
60
.
21.
Zemtsov
A.
,
Lorig
R.
,
Bergfield
W. F.
,
Bailin
P. L.
, and
Ng
T. C.
,
1989
, “
Magnetic Resonance Imaging of Cutaneous Melanocytic Lesions
,”
Journal of Dermatologic Surgery and Oncology
, Vol.
15
, pp.
854
858
.
22.
Zemtsov
A.
,
Lorig
R.
,
Ng
T. C.
,
Xue
M.
,
Bailin
P. L.
,
Bergfeld
W. F.
,
Larson
K.
, and
Yetman
R.
,
1991
, “
Magnetic Resonance Imaging of Cutaneous Neoplasms: Clinicopathologic Correlation
,”
Journal of Dermatologic Surgery and Oncology
, Vol.
17
, pp.
416
422
.
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