... particulates Jeffrey S. Newman1 COMBUSTION FIRE CHEMISTRY OF INDUSTRIAL FLUIDS REFERENCE: Newman, J. S., "Combustion Fire Chemistry of Industrial Fluids," Fire Resistance of industrial Fluids, ASTM STP 1284, George E. Totten and Jiirgen Reichel, Eds., American Society for Testing and Materials, Philadelphia...

..., polymeric debris and macrophages appear to be particularly reactive agents in the bone lysis phenomenon seen around contemporary total hip designs, but any particulate material small enough to be phagocytosed may contribute to this mechanism (metallics or ceramics). In addition to wear at the articulating...

... clinical and experimental research on the biology of aseptic loosening of joint arthroplasties and discusses the important role of particulate polymeric debris. particulates implants biomaterials polymethyl methacrylate polyethylene particles prosthetic loosening arthroplasty Stuart B...

... debris is generated. particulates implants arthroplasty wear debris histiocytes titanium polyethylene Pat Campbell, l S a m Nasser, 2 Nir Kossovsky, 3 and H. C. A m s t u t z 4 Histopathological Effects of UltrahighMolecular-Weight Polyethylene and Metal Wear Debris in Porous and Cemented...

... osteolysis appears to be mediated by histiocytes containing both metallic and polymeric wear debris. particulates implants osteolysis wear titanium polyethylene total hip replacement J. J. Jacobs, 1 R. M. Urba/l, 1 F. Schajowicz, 1 J. Gavri[ovic, 2 a n d J. O. Galantel Particulate-Associated...

... intracellular particulate polyethylene and metallic debris was found in three of the cases. In the fourth, there was a fine fibrous membrane lining a cystic cavity. Although the tissue in the fourth case contained occasional macrophages, foreign material could not be identified on light microscopy. On electron...

... arthroplasty failure. It is generally accepted that factors influencing the bioreactivity of tissue to debris include the amount (mass burden) of debris and the size, shape, and surface properties of the particles. There have been several qualitative studies of particulates visible by light microscopy in human...

... to be a clinically significant problem with cemented all-UHMWPE components, the use of metal-backed patellar components, by any technique or with any design, appears unwarranted. particulates implants metal-backed patella wear debris failure mechanism ultrahigh-molecular-weight polyethylene (UHMWPE...

... worrisome combination. Profile imaging is a useful additional tool for assessing design features of implants and their subsequent relationships to implant-generated wear debris. particulates implants total knee arthroplasty patellofemoral joint wear debris ultrahigh-molecular-weight polyethylene...

... for the development of the interface membrane but rather that one or more diverse, nonspecific, biologically indigestible wear particles, released at the bone/implant interface, trigger the self-perpetuating growth of the interface membrane. particulates implants arthroplasty internal fixation plate...

... in the periprosthetic bone lysis associated with aseptic loosening in humans. particulates implants polyethylene bulk bone prostaglandin E 2 interface animal model arthroplasty loosening S. B. Goodman, 1 R. C. Chin, 2 S. S. Chiou, 2 and J. S. Lee 1 Prostaglandin E2 Synthesis by the Tissue Surrounding...

... Evaluation of the biocompatibility of particulate debris is of paramount importance in improving the long-term results of joint replacement arthroplasty. This paper compares the results of intramuscular implants of particulates with the results of injection of particulates in the rat...

.... The authors used this model to investigate the differences in biological response to polymethyl methacrylate with and without barium sulfate, and found that the presence of barium sulfate led to a markedly increased inflammatory reaction. particulates implants biocompatibility polymethyl methacrylate...

... particles activate monocyte/macrophages to release prostaglandin E 2 (PGE 2 ) and directly stimulate fibroblasts to increase collagen synthesis. These observations provide a potential mechanism by which the release of metal particulate debris could induce a fibrous connective tissue reaction and focal bone...

.... There were no differences in IL-1 levels between the fabricated and retrieved bone cement particles. In this cell culture system, fibroblasts seem to be potent producers of PGE 2 secretion, regardless of the shape or size of the particles. particulates implants wear particles bone cement clinical...

... A preliminary study of the adsorption of plasma proteins to four commonly used arthroplastic materials was performed. Particulate forms of titanium, cobalt, chromium, and polymethyl methacrylate (PMMA) were incubated with plasma from patients undergoing primary arthroplastic surgery and from...

... be successfully evaluated by the concentration measurements, as exemplified in this paper. With this technique, the fretting wear aspects of new modular devices, including particulate and metal ion release issues, can be better addressed without making any major changes in existing testing protocols. The use...

... Biocompatibility testing of metallic materials should include implantation of particulate material of high purity and small size. Powder production of iron-, cobalt-, and titanium-based implant metal alloys was achieved by a method of gentle rubbing of metal bars in closed containers of the same...

... The objective of this study was to determine histologically the local and systemic soft tissue responses to polymeric particulate generated by mechanical degradation of prosthetic anterior cruciate ligament (ACL) devices in a canine model. Following gross observations at ligament retrieval...

... Wear particles released from synthetic anterior cruciate ligaments (ACLs) have been implicated as mediators of the effusions and synovitis that often follow ACL reconstruction. Particulate material, released as a result of abrasion and device failure, interacts with the synovial lining cells...