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ASTM Selected Technical Papers
Pesticide Formulations and Application Systems: 10th Volume
By
LE Bode,
LE Bode
1
University of Illinois
, Urbana, IL 61801
; symposium chairman and editor
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JL Hazen,
JL Hazen
2
BASF Corporation
, Research Triangle Park, NC 27502-3528
; symposium cochairman and editor
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DG Chasin
DG Chasin
3
ICI Chemicals
, Wilmington, DE 19897
; symposium cochairman and editor
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ISBN-10:
0-8031-1388-9
ISBN:
978-0-8031-1388-6
No. of Pages:
268
Publisher:
ASTM International
Publication date:
1990
eBook Chapter
The Role of Risk Assessment in the Regulation of Pesticides
By
NJ Rachman
NJ Rachman
1Dr. Rachman is a
Project Manager
at ENVIRON Corporation
, 4350 North Fairfax Drive, Arlington, Virginia 22203
.
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Page Count:
8
-
Published:1990
Citation
Rachman, N. "The Role of Risk Assessment in the Regulation of Pesticides." Pesticide Formulations and Application Systems: 10th Volume. Ed. Bode, L, Hazen, J, & Chasin, D. 100 Barr Harbor Drive, PO Box C700, West Conshohocken, PA 19428-2959 : ASTM International, 1990.
Download citation file:
Quantitative risk assessment is an important tool for regulating potentially carcinogenic chemicals including some pesticides. Although requiring that pesticide residue tolerances not exceed a specific dietary risk level may appear to be an effective risk management approach, it ignores significant limitations of calculated risk numbers that arise from uncertainties inherent in the risk assessment process. Determining what level of risk is to be considered negligible is a matter of policy rather than science. Different federal agencies and programs consider various levels of risk acceptable, but there appears to be some consensus that risks below 10-6 are negligible.
References
1.
Elements of Toxicology and Chemical Risk Assessment Revised
, ENVIRON Corp.
, Washington, DC
, 1988
.2.
National Academy of Sciences (NAS)
, Risk Assessment in the Federal Government, Managing the Process
, National Academy Press
, Washington, DC
, 1983
.3.
Rodricks
, J.V.
, Brett
, S. M.
, and Wrenn
, G. C.
, “Significant Risk Decisions in Federal Regulatory Agencies
,” Regulatory Toxicology and Pharmacology
, Vol. 7
, 1987
, pp. 307–320.4.
Rodricks
, J. V.
and Taylor
, M. R.
, “Application of Risk Assessment to Food Safety Decision-Making
,” Regulatory Toxicology and Pharmacology
, 1983
, pp. 275–307.5.
U.S. Environmental Protection Agency (USEPA)
, “Guidelines for Carcinogen Risk Assessment
,” Federal Register
, 51
: 33992–34003, 24
09
1986
.6.
U.S.Office of Science and Technology Policy (OSTP)
, “Chemical Carcinogens: A Review of the Science and Its Associated Principles
,” Federal Register
50
: 10371–10442, 14
03
1985
.
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