We investigate the mechanics of the detachment of an inclined micro-pillar adhered to a dissimilar substrate when subjected to a combination of an axial load and end moment. When the micro-pillar has adhered to the substrate, singular stress fields exist at the bi-material corners. The order of singularity is estimated using asymptotic analysis. The first two terms in the asymptotic expansion lead to singular stress fields. The magnitude of the singularity is evaluated in terms of the elastic mismatch between the pillar and substrate and the micro-pillar inclination. The asymptotic stress due to the moment loading is more sensitive to the micro-pillar inclination when compared to that due to the axial loading. They are insensitive to the micro-pillar inclination when the micro-pillar is rigid when compared to the substrate. A short interfacial crack is further assumed to exist at the bi-material corner. This crack is embedded in the corner singularity region and is loaded by the singular fields due to axial and bending loads. A boundary layer analysis is performed on the singular zone to estimate the stress intensity factor when a short crack embedded in it is subjected to the singular fields. The stress intensity factors are also calculated for a long interfacial crack at the bi-material corner, which extends beyond the singular zone. By using the aforementioned results, we investigate the detachment of the inclined micro-pillar under the combination of an axial load and end moment.