In earlier studies on stress distribution in arteries, a monolayer wall model was often used. An arterial wall consists of three layers, the intima, the media, and the adventitia. The intima is mechanically negligible as a stress supporting layer against the blood pressure in young healthy vessels, although it is important as an interface between blood and arterial wall. The media and adventitia layers are considered to support blood pressure. Recently, residual strain and a constitutive law for porcine coronary arteries have been investigated in separated media and adventitia. Using the data obtained through these investigations, a stress analysis considering residual stress (strain) in each layer was performed in this study, and residual strain and stress were computed for a bilayer model. The circumferential residual stress was compressive in the inner region, tensile in the outer region, and had discontinuity at the boundary between the media and adventitia. A peak circumferential stress occurred in the media at the boundary between the media and adventitia under a physiological condition, and an almost flat distribution was obtained in the adventitia. This pattern does not change under a hypertensive condition. These results suggest that a remodeling with hypertension occurs in the media.

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