Formulas for the tensile, compressive, and shear strengths along an axis off the grain axis of a material with orthotropic symmetry are derived from the quadratic form of the Tsai-Wu strength theory. The results are compared with some shear strength data on wood and they are applied to data on human femoral bone and bovine Haversian bone. A strength criterion consistent with the Tsai-Wu theory and with the existing experimental strength data on bone is identified.

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